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Immobilization of Cells by Magnetic Nanoparticles

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Immobilization of Enzymes and Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 2100))

Abstract

Cell harvesting is one of the main expensive, labor-intensive, and energy-consuming steps in downstream processing. Cell immobilization has introduced as a valuable strategy for process intensification in biotechnological industries. Here we describe magnetic immobilization as a promising and novel technique for cell immobilization by using magnetic nanoparticles. This technique is based on the decoration of cells with magnetic nanoparticles to make them sensitive to magnetic field. So, the cells can be harvested simply by applying a magnetic separator.

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References

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Acknowledgment

This study was supported by a collaboration between Shiraz university of Medical Sciences and The University of Waikato (New Zealand).

Author information

Authors and Affiliations

  1. Department of Medical Nanotechnology, School of Advanced Medical Sciences and Technologies, Shiraz University of Medical Sciences, Shiraz, Iran

    Alireza Ebrahiminezhad

  2. Department of Pharmaceutical Biotechnology, School of Pharmacy and Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran

    Alireza Ebrahiminezhad, Seyedeh-Masoumeh Taghizadeh & Younes Ghasemi

  3. Faculty of Science and Engineering, The University of Waikato, Hamilton, New Zealand

    Aydin Berenjian

Authors
  1. Alireza Ebrahiminezhad
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  2. Seyedeh-Masoumeh Taghizadeh
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  3. Younes Ghasemi
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  4. Aydin Berenjian
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Corresponding authors

Correspondence to Alireza Ebrahiminezhad or Aydin Berenjian .

Editor information

Editors and Affiliations

  1. CSIC Campus Cantoblanco, Instituto de Catalisis, Madrid, Spain

    Jose M. Guisan

  2. Institute of Biotech and Biochemical Engineering, Graz University of Technology, Graz, Austria

    Juan M. Bolivar

  3. CIC biomaGUNE, Donostia-San Sebastian, Spain

    Fernando López-Gallego

  4. Campus UAM-CSIC, Institute of Catatalysis, Madrid, Spain

    Javier Rocha-Martín

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Ebrahiminezhad, A., Taghizadeh, SM., Ghasemi, Y., Berenjian, A. (2020). Immobilization of Cells by Magnetic Nanoparticles. In: Guisan, J., Bolivar, J., López-Gallego, F., Rocha-Martín, J. (eds) Immobilization of Enzymes and Cells. Methods in Molecular Biology, vol 2100. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0215-7_29

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  • DOI: https://doi.org/10.1007/978-1-0716-0215-7_29

  • Published:

  • Publisher Name: Humana, New York, NY

  • Print ISBN: 978-1-0716-0214-0

  • Online ISBN: 978-1-0716-0215-7

  • eBook Packages: Springer Protocols

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