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Decellularized Bone Matrix Scaffold for Bone Regeneration

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Book cover Decellularized Scaffolds and Organogenesis

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1577))

Abstract

Decellularized bone matrix is gaining a lot of attention as implantable biomaterials and/or biological scaffolds for bone tissue repair, and shows good clinical performance. This chapter describes the processing techniques and characterization protocols of decellularized bone. For the applications of the decellularized bone scaffold in promoting bone repair and regeneration, we discuss some of the current advances, and highlight the advantages and disadvantages of these scaffolds. Fabrication and application of the hydrogel derived from decellularized bone for bone tissue engineering are also presented.

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Acknowledgements

This work was supported in part by grants from the National Natural Science Foundation of China (11672051), the China Postdoctoral Science Foundation (2015M582521), and the Fundamental Research Funds for the Central Universities (106112017CDJQJ468823).

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Authors and Affiliations

  1. Key Laboratory of Biorheological Science and Technology (Chongqing University), Ministry of Education, Bioengineering College, Chongqing University, Chongqing, 400044, People’s Republic of China

    Guobao Chen & Yonggang Lv

  2. Mechanobiology and Regenerative Medicine Laboratory, Bioengineering College, Chongqing University, 174 Shazheng Street, Shapingba District, Chongqing, 400044, People’s Republic of China

    Guobao Chen & Yonggang Lv

Authors
  1. Guobao Chen
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  2. Yonggang Lv
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Corresponding author

Correspondence to Yonggang Lv .

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Editors and Affiliations

  1. Ottawa Hospital Research Institute, Ottawa, ON, Canada

    Kursad Turksen

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Chen, G., Lv, Y. (2017). Decellularized Bone Matrix Scaffold for Bone Regeneration. In: Turksen, K. (eds) Decellularized Scaffolds and Organogenesis. Methods in Molecular Biology, vol 1577. Humana Press, New York, NY. https://doi.org/10.1007/7651_2017_50

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  • DOI: https://doi.org/10.1007/7651_2017_50

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-7655-3

  • Online ISBN: 978-1-4939-7656-0

  • eBook Packages: Springer Protocols

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