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Application of Decellularized Tissue Scaffolds in Ovarian Tissue Transplantation

Part of the Methods in Molecular Biology book series


In tissue engineering, decellularized scaffolds have been proved to have remarkable capacity to promote regeneration in various organs such as kidney, heart, lung, and liver. Marrying the field of cryobiology and reproductive medicine resulted in considerable progress and breakthroughs, which led to the emergence of ovarian tissue cryopreservation and transplantation as a promising option for fertility preservation. Here we describe an innovative application of decellularized tissue scaffolds as a regenerative platform for reconstruction of ovarian grafts for auto-transplantation.


Cryopreservation Decellularized tissue scaffold Extracellular tissue matrix Fertility preservation Ovarian tissue transplantation 



K.O. is supported by Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD—RO1HD053112 and R21HD061259) and National Cancer Institute (NCI).


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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Innovation Institute for Fertility Preservation and In Vitro FertilizationNew YorkUSA
  2. 2.Laboratory of Molecular Reproduction and Fertility Preservation, Department of Obstetrics and GynecologyNew York Medical CollegeValhallaUSA

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