Part of the series Methods in Molecular Biology pp 1-8


Monitoring of Paternal Mitochondrial Degradation in Caenorhabditis elegans

  • Miyuki SatoAffiliated withLaboratory of Molecular Membrane Biology, Institute for Molecular and Cellular Regulation, Gunma University Email author 
  • , Ken SatoAffiliated withLaboratory of Molecular Traffic, Institute for Molecular and Cellular Regulation, Gunma University

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In Caenorhabditis elegans embryos, paternally inherited mitochondria and their mitochondrial DNA are degraded via selective autophagy called allophagy (allogeneic organelle autophagy). This is a developmentally programmed autophagy and combined with C. elegans genetics and in vivo imaging provides a unique opportunity to analyze selective autophagy under physiological conditions.


C. elegans Allophagy Autophagy Mitochondria Mitochondrial DNA Maternal inheritance