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Monitoring of Paternal Mitochondrial Degradation in Caenorhabditis elegans

Protocol
Part of the Methods in Molecular Biology book series

Abstract

In Caenorhabditis elegans embryos, paternally inherited mitochondria and their mitochondrial DNA are degraded via selective autophagy called allophagy (allogeneic organelle autophagy). This is a developmentally programmed autophagy and combined with C. elegans genetics and in vivo imaging provides a unique opportunity to analyze selective autophagy under physiological conditions.

Keywords:

C. elegans Allophagy Autophagy Mitochondria Mitochondrial DNA Maternal inheritance 

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Copyright information

© Springer Science+Business Media New York 2017

Authors and Affiliations

  1. 1.Laboratory of Molecular Membrane Biology, Institute for Molecular and Cellular RegulationGunma UniversityMaebashiJapan
  2. 2.Laboratory of Molecular Traffic, Institute for Molecular and Cellular RegulationGunma UniversityMaebashiJapan

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