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Mesoderm Differentiation from hiPS Cells

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Book cover Induced Pluripotent Stem (iPS) Cells

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1357))

Abstract

Human induced pluripotent stem (hiPS) cells are very attractive tools for modeling diseases and regenerative medicine. However, to achieve them, the efficient differentiation methods of hiPS cells into aimed cell type in vitro are necessary. Because mesoderm cells are useful in particular, we have developed the differentiation of mouse embryonic stem (mES) cells into mesoderm cells previously. In this time, these methods were improved for hiPS cells and now human mesoderm cells are able to be obtained efficiently. It is certain that the new methods are applicable to various studies and therapies.

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Acknowledgment

This work was supported in part by grants from the Ministry of Health, Labour, and Welfare of Japan and Core Research for Evolutional Science and Technology (CREST), Japan Science and Technology Agency.

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Authors and Affiliations

  1. Kumamoto University, 2-39-1 Kurokami, Chuo-Ku, Kumamoto, 860-8555, Japan

    Hiroyuki Miwa & Takumi Era

Authors
  1. Hiroyuki Miwa
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  2. Takumi Era
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Corresponding author

Correspondence to Hiroyuki Miwa .

Editor information

Editors and Affiliations

  1. Ottawa Hospital Research Institute, Ottawa, Ontario, Canada

    Kursad Turksen

  2. Mount Sinai Hospital Samuel Lunenfeld Research Inst, Toronto, Ontario, Canada

    Andras Nagy

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© 2014 Springer Science+Business Media New York

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Miwa, H., Era, T. (2014). Mesoderm Differentiation from hiPS Cells. In: Turksen, K., Nagy, A. (eds) Induced Pluripotent Stem (iPS) Cells. Methods in Molecular Biology, vol 1357. Humana Press, New York, NY. https://doi.org/10.1007/7651_2014_162

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  • DOI: https://doi.org/10.1007/7651_2014_162

  • Published:

  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-3054-8

  • Online ISBN: 978-1-4939-3055-5

  • eBook Packages: Springer Protocols

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