Antibiotic Resistance Evaluation of Yersinia pestis

  • Jingyu Guo
Part of the Springer Protocols Handbooks book series (SPH)


Yersinia pestis is the causative agent of plague and has the potential for use as a biological weapon. Y. pestis clinical isolates that are resistant to all antimicrobial agents recommended for plague therapy have been found. Therefore, standardized methods should be established to detect emerging drug-resistant Y. pestis strains. In this chapter, three microbial susceptibility testing methods (disk diffusion, E test, and broth microdilution) are introduced, including the Clinical and Laboratory Standards Institute reference method for susceptibility testing of Y. pestis (broth microdilution).

Key words

Yersinia pestis Disk diffusion E test Broth microdilution 


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Copyright information

© Springer Nature Singapore Pte Ltd. 2018

Authors and Affiliations

  • Jingyu Guo
    • 1
  1. 1.Department of Clinical LaboratoryThe 316th Hospital of PLABeijingChina

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