Pyridylethylation of Cysteine Residues
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To help maintain their three-dimensional structure, many proteins contain disulfide bridges between cysteine residues. Cysteine residues can cause problems during Edman sequence analysis, and quantification of cysteine and cystine by amino acid analysis is difficult since these residues are unstable during acid hydrolysis.
KeywordsCysteine Residue Amino Acid Analysis Disulfide Bridge Laser Desorption Ionization Guanidine Hydrochloride
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