Molecularly Imprinted Polymer Thin-Film Electrochemical Sensors

  • Vera L. V. Granado
  • M. Teresa S. R. Gomes
  • Alisa Rudnitskaya
Part of the Methods in Molecular Biology book series (MIMB, volume 2027)


Preparation of potentiometric and amperometric sensors with thin-film membranes based on molecularly imprinted polymers (MIP) is described. Spherical MIP microparticles with diameter below 1 μm are suitable for incorporation into the sensing membrane by the deposition of a conducting polymer on the electrode surface. This is achieved through electropolymerization from the suspension of MIP particles in monomer solution. Procedures of the synthesis of MIP particles, preparation of sensing membranes, and analytical application of potentiometric and amperometric sensors with MIP-modified membranes are described.

Key words

Molecularly imprinted polymers Precipitation polymerization Potentiometric sensors Amperometric sensors Electropolymerization Conducting polymers Plasticized polyvinyl chloride 



The authors thank CESAM (UID/AMB/50017—POCI-01-0145-FEDER-007638), FCT/MCTES through national funds (PIDDAC) for financial support, as well as FEDER for providing co-funding within the PT2020 Partnership Agreement and Compete 2020. A. Rudnitskaya wishes to acknowledge postdoctoral fellowship SFRH/BPD/104265/2014 supported by FCT.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  • Vera L. V. Granado
    • 1
  • M. Teresa S. R. Gomes
    • 1
    • 2
  • Alisa Rudnitskaya
    • 1
    • 2
  1. 1.Chemistry DepartmentUniversity of AveiroAveiroPortugal
  2. 2.CESAMUniversity of AveiroAveiroPortugal

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