Compositional Analysis of the Human Microbiome in Cancer Research

  • Elisa Morales
  • Jun Chen
  • K. Leigh GreathouseEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1928)


Gut microbial composition has shown to be associated with obesity, diabetes mellitus, inflammatory bowel disease, colitis, autoimmune disorders, and cancer, among other diseases. Microbiome research has significantly evolved through the years and continues to advance as we develop new and better strategies to more accurately measure its composition and function. Careful selection of study design, inclusion and exclusion criteria of participants, and methodology are paramount to accurately analyze microbial structure. Here we present the most up-to-date available information on methods for gut microbial collection and analysis.

Key words

Metagenomic sequencing Gut microbiota Taxonomic classification Cancer research 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Robbins College of Health and Human SciencesBaylor UniversityWacoUSA
  2. 2.Division of Biomedical Statistics and InformaticsDepartment of Health Sciences Research, Mayo ClinicRochesterUSA

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