Osteoarthritis Mouse Model of Destabilization of the Medial Meniscus

  • Antonia Sophocleous
  • Carmen HuesaEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1914)


This chapter describes the surgical procedure for destabilization of medial meniscus in mice. Details on subsequent microCT and histological analysis are also provided, as well as details on osteoarthritis evaluation.

Key words

Destabilization of medial meniscus DMM Osteoarthritis MicroCT Histological analysis 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Life Sciences, School of ScienceEuropean University CyprusNicosiaCyprus
  2. 2.Centre for Reproductive Health, The Queen’s Medical Research InstituteUniversity of EdinburghScotlandUK
  3. 3.Centre for Musculoskeletal Science, Anderson CollegeUniversity of GlasgowGlasgowUK

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