Ovariectomy/Orchiectomy in Rodents

  • Antonia Sophocleous
  • Aymen I. IdrisEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1914)


This chapter describes the surgical procedures for ovariectomy and orchiectomy in mice and rats. In addition to providing technical details of the surgical techniques, details of anesthesia options and pre-, peri-, and postoperative care are also included.

Key words

Surgery Ovariectomy Orchiectomy Oestrogen Androgen Rodents Mouse Rat Bone loss Resorption 


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Department of Life Sciences, School of SciencesEuropean University CyprusNicosiaCyprus
  2. 2.Department of Oncology and MetabolismUniversity of SheffieldSheffieldUK

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