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Drosophila Genetics: Analysis of Tissue Growth in Adult Tissues

  • Alexander D. Fulford
  • Paulo S. RibeiroEmail author
Protocol
Part of the Methods in Molecular Biology book series (MIMB, volume 1893)

Abstract

Drosophila melanogaster has been widely used in the study of developmental growth control and has been instrumental in the discovery and delineation of many signalling pathways that contribute to this growth, in particular the Hippo pathway. Quantitative analysis of adult tissue size has remained a vital tool in the study of tissue growth. This chapter will describe how to dissect, image, and quantify two tissues commonly used to measure growth, the Drosophila wing and eye.

Key words

Drosophila Adult eye Adult wing SEM Tissue growth 

Notes

Acknowledgments

We thank Maxine Holder and Nic Tapon for comments on the manuscript. This work was supported by funding from Cancer Research UK (C16420/A18066) and from The Academy of Medical Sciences/Wellcome Trust Springboard Award (SBF001/1018).

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2019

Authors and Affiliations

  1. 1.Centre for Tumour Biology, Barts Cancer Institute, Queen Mary University of LondonLondonUK

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