Prenatal exposure to various environmental teratogens such as drugs, toxins, and infectious etiologies results in a wide range of developmental abnormalities, including growth deficiency, developmental delay, structural defects, functional CNS abnormalities, and fetal death. Here, we describe the use of Drosophila melanogaster as a model organism for investigating teratogenic effects on embryonic development.
Teratogen DrosophilaEmbryonic cell culture Development Immunostaining
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This work was supported by grants from National Natural Science Foundation of China (Grant No. 31771437, 31501165, and 31271480), and Hundred Talent program of Chinese Academy of Sciences, Pandeng scholarship of Liaoning province and Qizhen Gongcheng from Dalian Medical University to X.B.
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