Effect of Teratogens on Development of Drosophila melanogaster

  • Dong Li
  • Xiaolin BiEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 1797)


Prenatal exposure to various environmental teratogens such as drugs, toxins, and infectious etiologies results in a wide range of developmental abnormalities, including growth deficiency, developmental delay, structural defects, functional CNS abnormalities, and fetal death. Here, we describe the use of Drosophila melanogaster as a model organism for investigating teratogenic effects on embryonic development.

Key words

Teratogen Drosophila Embryonic cell culture Development Immunostaining 



This work was supported by grants from National Natural Science Foundation of China (Grant No. 31771437, 31501165, and 31271480), and Hundred Talent program of Chinese Academy of Sciences, Pandeng scholarship of Liaoning province and Qizhen Gongcheng from Dalian Medical University to X.B.


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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  1. 1.Department of Biological Sciences, College of Basic Medical SciencesDalian Medical UniversityDalianChina
  2. 2.Institute of Cancer Stem CellCancer Center, Dalian Medical UniversityDalianChina

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