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Stereotaxic Injection into the Rat Spinal Cord

  • Charla C. Engels
  • Piotr WalczakEmail author
Protocol
  • 924 Downloads
Part of the Neuromethods book series (NM, volume 116)

Abstract

Spinal cord is a frequent target for injection of various therapeutic agents including stem cells, growth factors, small molecules, or genetic constructs. Due to its fragility and specific anatomical localization injection has to be performed with great deal of care to minimize injury and assure precision of targeting. This chapter describes two approaches for gaining access to the spinal cord facilitating safe and efficient intraspinal injection.

Key words

Stereotaxy Spinal cord Rat Neurosurgery 

Supplementary material

Supplementary Video 1

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Division of MR Research, Russell H. Morgan Department of Radiology and Radiological Science, Cellular Imaging SectionInstitute for Cell Engineering, The Johns Hopkins University School of MedicineBaltimoreUSA
  2. 2.Division of MR Research, Russell H. Morgan Department of Radiology and Radiological Science, Cellular Imaging SectionInstitute for Cell Engineering, The Johns Hopkins University School of MedicineBaltimoreUSA
  3. 3.Department. of Radiology, Faculty of Medical SciencesUniversity of Warmia and MazuryOlsztynPoland

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