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Aging pp 57-65 | Cite as

Mouse Fitness as Determined Through Treadmill Running and Walking

  • Joseph C. Reynolds
  • Changhan LeeEmail author
Protocol
  • 155 Downloads
Part of the Methods in Molecular Biology book series (MIMB, volume 2144)

Abstract

Endurance testing simultaneously assesses a wide variety of physiological systems including the cardiovascular, respiratory, metabolic, and neuromuscular systems (Gabriel and Zierath, Cell Metab 25:1000–1011, 2017). Treadmill running is a noninvasive method to evaluate fitness capacity in a longitudinal or cross-sectional manner. High-intensity exercise tests can be used to determine peak physical capacity in mice. However, because aging is associated with a progressive loss of physical capacity the running protocols can be adapted and optimized for aged mice.

Key words

Mice Fitness Running Treadmill Aging 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Leonard Davis School of GerontologyUniversity of Southern CaliforniaLos AngelesUSA
  2. 2.USC Norris Comprehensive Cancer CenterLos AngelesUSA
  3. 3.Biomedical Science, Graduate SchoolAjou UniversitySuwonSouth Korea

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