Biobanking for Esophageal Squamous Cell Carcinoma

  • Alfred K. LamEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 2129)


Biobanking is important and fundamental for research and personalized medicine in patients with esophageal squamous cell carcinoma. The process often involves prospective collection of surgically obtained tissues (tissue banking) as well as serial blood samples (liquid biopsies) from the patients with esophageal squamous cell carcinoma. Apart from frozen tissues, formalin-fixed paraffin-embedded tissues are important sources of translational research. Careful planning and selection of the region of the paraffin-embedded tissues will maximize the use of tissue for molecular studies. Both cancer and non-cancer samples (controls) could be collected. The success and sustainability of the process needs proper infrastructure, advanced planning, funding, and multidisciplinary collaborations. The understanding of the principles and issues are detrimental for the success of biobanking. The technical procedures involved are standardized, complex, and time-consuming and needs coordinated taskforce.

Key words

Esophagus Tissue banking Squamous carcinoma Biobank Blood 


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© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Cancer Molecular Pathology of School of MedicineGriffith UniversityGold CoastAustralia

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