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Macroscopic Assessment and Sampling of Endoscopic Resection Specimens for Squamous Epithelial Malignancies with Superficial Involvement of Esophagus

  • Satoshi FujiiEmail author
  • Alfred K. LamEmail author
Protocol
  • 62 Downloads
Part of the Methods in Molecular Biology book series (MIMB, volume 2129)

Abstract

Endoscopic resection is commonly used for superficial squamous cell carcinoma or high-grade dysplasia of esophageal squamous cell carcinoma. The depth of invasion, clearance from resection margins, and other pathological parameters are important parameters to be examined. The depth of invasion by carcinoma is associated with the risk of lymph node metastases. In endoscopic resection of superficial squamous malignancies of the esophagus, proper pathological examination of the resected specimen could guide the management of the patients in terms of the need for additional treatment, including lymph node dissection, chemotherapy, and radiation therapies.

Key words

Endoscopic resection Pathology Dysplasia Esophageal Early squamous carcinoma 

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Division of PathologyExploratory Oncology Research & Clinical Trial Center, National Cancer CenterKashiwaJapan
  2. 2.Cancer Molecular Pathology of School of MedicineGriffith UniversityGold CoastAustralia

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