In Vivo Models for Pathotyping and Vaccine Efficacy for Swine Influenza

  • Kelly M. LagerEmail author
  • Amy L. Vincent
Part of the Methods in Molecular Biology book series (MIMB, volume 2123)


Swine influenza is a disease of the respiratory tract caused by influenza A virus (IAV). Experimental inoculation of pigs involves either aerosolization of virus and inhalation or the direct introduction of virus into the upper or lower respiratory tract. This chapter covers methods for experimental IAV infection of pigs and collection of specific samples to study the pathogenesis of swine influenza and vaccine efficacy.

Key words

Swine Influenza Experimental model Nasal swab Pathogenesis 


  1. 1.
    Zimmerman J, Karriker L, Ramirez A, Schwartz K, Stevenson G (eds) (2012) Diseases of swine, 10th edn. Blackwell, AmesGoogle Scholar

Copyright information

© This is a U.S. government work and not under copyright protection in the U.S.; foreign copyright protection may apply. 2020

Authors and Affiliations

  1. 1.Virus and Prion Research UnitUS Department of Agriculture, Agricultural Research Service, National Animal Disease CenterAmesUSA

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