Interleukin-1 (IL-1) Immunohistochemistry Assay in Oral Squamous Cell Carcinoma

  • Takaaki KamataniEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 2108)


This section describes an immunohistochemistry method to analyze interleukin-1 (IL-1) in oral squamous cell carcinoma. The described protocol has been optimized for IL-1 detection in formalin-fixed, paraffin-embedded oral tissue sections by light microscopy. A few common pitfalls and problems associated with immunohistochemical staining are discussed.

Key words

Immunohistochemistry Interleukin-1 Oral squamous cell carcinoma Formalin fixation Paraffin embedding 


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© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  1. 1.Department of Oral and Maxillofacial SurgeryShowa University School of DentistryOta-CityJapan

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