Molecular Modeling of the Interaction Between Stem Cell Peptide and Immune Receptor in Plants

  • Muhammad Naseem
  • Mugdha Srivastava
  • Ozge Osmanoglu
  • Jibran Iqbal
  • Fares M. Howari
  • Fatima A. AlRemeithi
  • Thomas DandekarEmail author
Part of the Methods in Molecular Biology book series (MIMB, volume 2094)


Molecular docking enables comprehensive exploration of interactions between chemical moieties and proteins. Modeling and docking approaches are useful to determine the three-dimensional (3D) structure of experimentally uncrystallized proteins and subsequently their interactions with various inhibitors and activators or peptides. Here, we describe a protocol for carrying out molecular modeling and docking of stem cell peptide CLV3p on plant innate immune receptor FLS2.

Key words

FLS2 CLV3p Docking Modeling Structure prediction Protein peptide interaction 



We thank the German Research Foundation (DFG) for funding (TR124/B1) to TD and start-up grant (R18045) by Zayed University to MN and UAE Space Agency grant (EU1804) to FMH.


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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2020

Authors and Affiliations

  • Muhammad Naseem
    • 1
    • 2
  • Mugdha Srivastava
    • 2
  • Ozge Osmanoglu
    • 2
  • Jibran Iqbal
    • 1
  • Fares M. Howari
    • 1
  • Fatima A. AlRemeithi
    • 1
  • Thomas Dandekar
    • 2
    Email author
  1. 1.Department of Life and Environmental Sciences, College of Natural and Health SciencesZayed UniversityAbu DhabiUAE
  2. 2.Department of Bioinformatics, BiocenterUniversity of WuerzburgWuerzburgGermany

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