Skip to main content

Metal Carcinogenesis In Experimental Animals

  • Protocol
Book cover Metal Carcinogenesis Testing

Part of the book series: Biological Methods ((BM))

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Protocol
USD 49.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Osswald, H., and K. Goerttler, Arsenic-induced leukoses in mice after diaplacental and postnatal application. Verb. Dtsch. Ges. Path. 55: 289–293, 1971.

    CAS  Google Scholar 

  2. Milner, J. E., The effect of ingested arsenic on methylcholanthrene-induced skin tumors in mice. Arch. Environ. Health 18: 7–11, 1969.

    PubMed  CAS  Google Scholar 

  3. Hueper, W. C., and W. W. Payne, Experimental studies in metal carcinogenesis. Chromium, nickel, iron, and arsenic. Arch. Environ. Health 5: 445–562, 1962.

    PubMed  CAS  Google Scholar 

  4. Frost, D. V., Arsenicals in biology—retrospect and prospect. Fed. Proc. 26: 194–208, 1967.

    PubMed  CAS  Google Scholar 

  5. Lucis, O. J., R. Lucis, and K. Aterman, Tumorigenesis by cadmium. Oncology 26: 53–67, 1972.

    Article  PubMed  CAS  Google Scholar 

  6. Heath, J. C., M. Webb, and M. Caffrey, The interaction of carcinogenic metals with tissues and body fluids. Cobalt and horse serum. Brit. J. Cancer 23: 153–166, 1969.

    Article  PubMed  CAS  Google Scholar 

  7. Reddy, J., D. Svoboda, D. Azarnoff, and R. Dawas, Cadmium-induced Leydig cell tumors of rat testis: Morphologic and cytochemical study. J. Nat. Cancer Inst. 51: 891–903, 1973.

    PubMed  CAS  Google Scholar 

  8. Haddow, A., F. J. C. Roe, C. E. Dukes, and B. C. V. Mitchley, Cadmium neoplasia: Sarcomata at the site of injection of cadmium sulphate in rats and mice. Brit. J. Cancer 18: 667–673, 1964.

    Article  PubMed  CAS  Google Scholar 

  9. Laskin, S., M. Kuschner, and R. T. Drew, Studies in pulmonary carcinogenesis. In: Inhalation carcinogenesis, eds. M. G. Hanna, Jr., Nettesheim, and J. R Gilbert, Washington, D.C., Atomic Energy Commission, 1970, pp. 321–351.

    Google Scholar 

  10. Kuschner, M., and S. Laskin, Experimental models in environmental carcinogenesis. Amer. J. Path. 64: 183–191, 1971.

    PubMed  CAS  Google Scholar 

  11. Nettesheim, P., M. G. Hanna, Jr., D. G. Dohertz, R. F. Newell, and A. Hellman, Effect of calcium chromate dust, influenza virus, and 100 R whole-body x-radiation on lung tumor incidence in mice. J. Nat. Cancer Inst. 47: 1129–1144, 1971.

    PubMed  CAS  Google Scholar 

  12. Vollmann, J., Tierexperimente mit intraossarem Arsen-, Chrom-, and Kobaltdepot. Schweiz. A. Allg. Path. Bakt. 2: 440–443, 1940.

    Google Scholar 

  13. Payne, W. W., Production of cancers in mice and rats by chromium compounds. Arch. Industri. Health 21: 530–535, 1960.

    CAS  Google Scholar 

  14. Roe, F. J. C, and R. L. Carter, Chromium carcinogenesis: Calcium chromate as a potent carcinogen for the subcutaneous tissues of the rat. Brit. J. Cancer 23; 172–176, 1969.

    Article  PubMed  CAS  Google Scholar 

  15. Gilman, J. P. W., Metal carcinogenesis. II. A study on the carcinogenic activity of cobalt, copper, iron, and nickel compounds. Cancer Res. 22: 158–162, 1962.

    PubMed  CAS  Google Scholar 

  16. Thomas, J. A., and J. P. Thiery, Production elective de liposarcoma chez les lapins par les oligoelements zinc et cobalt. Compt. Rendu. Hebd. Seanc. Acad. Sci. (Paris) 236: 1387, 1953.

    CAS  Google Scholar 

  17. Hueper, W. C., Experimental studies in metal carcinogenesis. IX. Pulmonary lesions in guinea pigs and rats exposed to prolonged inhalation of powdered metallic nickel. Arch. Path. 65: 600–607, 1958.

    CAS  Google Scholar 

  18. Toda, M., Experimental studies of occupational lung cancer. Bull. Tokyo Med. Dent. Univ. 9: 440–441, 1962.

    Google Scholar 

  19. Campbell, J. A., Lung tumors in mice and men. Brit. Med. J. 1: 179–183, 1943.

    Article  PubMed  Google Scholar 

  20. Sunderman, F. W., Jr., Metastasizing pulmonary tumors in rats induced by the inhalation of nickel carbonyl. In: Lung Tumors in Animals, ed. L. Severi, Proc. of Third Quadrennial Conference on Cancer, Perugia, Italy. Perugia, Division of Cancer Research, 1966, pp. 551–564.

    Google Scholar 

  21. Gilman, J. P. W., M. R. Daniel, and P. K. Basrur, Observations of tissue selectivity in nickel tumorigenesis. Proc. Amer. Ass. Cancer Res. 7: 24, 1966.

    Google Scholar 

  22. Hebert, G. J., P. K. Basrur, and J. P. W. Gilman, Arginase activity in nickel sulfide-induced rat tumors. Cancer 25: 1134–1141, 1970.

    Article  PubMed  CAS  Google Scholar 

  23. Jasmin, G., Effects of methandrostenolone on muscle carcinogenesis induced in rats by nickel sulphide. Brit, J. Cancer 17: 681–686, 1963.

    Article  CAS  Google Scholar 

  24. Heath, J. C, and M. R. Daniel, The production of malignant tumours by nickel in the rat. Brit. J. Cancer 18: 261–264, 1964.

    Article  PubMed  CAS  Google Scholar 

  25. Webb, M., J. C. Heath, and T. Hopkins, Intranuclear distribution of the inducing metal in primary rhabdomyosarcomata induced in the rat by nickel, cobalt, and cadmium. Brit. J. Cancer 26: 274–278, 1972.

    Article  PubMed  CAS  Google Scholar 

  26. Sunderman, F. W., Jr. Metal carcinogenesis. In: Chemical Diagnosis of Disease, eds., Brown, Mitchell, and Young. Elsevier, Amsterdam: Hemisphere 1975, 1–39.

    Google Scholar 

  27. Sunderman, F. W., Jr., and R. M. Maenza, Comparisons of carinogenicities of nickel compounds in rats. Res. Commun. Chem. Pathol. Pharmocol. 14: 319–330, 1976.

    CAS  Google Scholar 

  28. Jasmin, G., and J. L. Riopelle, Renal carcinomas and erythrocytosis in rats following intrarenal injection of nickel subsulfide. Lab. Invest. 35: 71–78, 1976.

    PubMed  CAS  Google Scholar 

  29. Lau, T. J., R. L. Hackett, and F. W. Sunderman, Jr., The carcinogenicity of intravenous nickel carbonyl in rats. Cancer Res. 32: 2253–2258, 1972.

    PubMed  CAS  Google Scholar 

  30. Maenza, R. M., A. M. Pradhan, and F. W. Sunderman, Jr., Rapid induction of sarcomas in rats by a combination of nickel sulfide and 3,4-benzpyrene. Cancer Res. 31: 2067–2071, 1971.

    PubMed  CAS  Google Scholar 

  31. Kasprzak, K. S., L. Marchow, and J. Breborowicz, Pathological reactions in rat lungs following intratrachial injection of nickel subsulfide and 3,4-benzpyrene. Res. Commun. Chem. Path. Pharmacol. 6: 237–245, 1973.

    CAS  Google Scholar 

  32. Michalowksy, I., Die experimentelle Erzeugung einer teratoiden Neubildung der Hoden beim Hahn. Vorlaufige Mitteilung. Zentbl. Allg. Path. Anat. 38: 585–587, 1926.

    Google Scholar 

  33. Bresler, W. M., On the dynamics of blastomogenesis in the testis. Acta Unio Intern. Contra. Cancrum 20: 1501–1503, 1964.

    CAS  Google Scholar 

  34. Guthrie, J., and D. A. Guthrie, Embryonal carcinomas in Syrian hamsters after intratesticular inoculation of zinc chloride during seasonal testicular growth. Cancer Res. 34: 2612–2614, 1974.

    PubMed  CAS  Google Scholar 

  35. Gunn, S. A., T. C. Gould, and W. A. D. Anderson, Effect of zinc on carcinogenesis by cadmium. Proc. Soc. Exp. Biol. Med. 115: 653–657, 1964.

    PubMed  CAS  Google Scholar 

  36. Heath, J. C., M. R. Daniel, J. T. Dingle, and M. Webb, Cadmium as a carcinogen. Nature 193: 592–593, 1962.

    Article  PubMed  CAS  Google Scholar 

  37. Haddow, A., F. J. C. Roe, and B. C. V. Mitchley, Induction of sarcomata in rabbits by intramuscular injection of iron-dextran (“Infer-on”). Brit. Med. J. 1: 1593–1594, 1964.

    Article  PubMed  CAS  Google Scholar 

  38. Neukomm, S., Recherches sur le pouvoir cancerigene et co-cancerigene de diverses preparations a base de fer. Proc. Europ. Soc. Drug Toxicity 2: 174–177, 1969.

    Google Scholar 

  39. Langvad, E., Iron-dextran induction of distant tumors in mice. Int. J. Cancer 3: 415–423, 1968.

    Article  PubMed  CAS  Google Scholar 

  40. Haddow, A., and E. S. Horning, On the carcinogenicity of an iron-dextran complex. J. Nat. Cancer Inst. 24: 109–147, 1960.

    PubMed  CAS  Google Scholar 

  41. Zollinger, H. U., Durch chronische Bleivergiftung erzeugte Nieren-adenome und-carcinome bei Ratten und ihre Beziehungen zu den entsprechenden Neubildungen des Menschen. Virchows Arch. Path. Anat. 323: 694–710, 1953.

    Article  CAS  Google Scholar 

  42. Zawirska, B., and K. Medras, Morphology and biological activity of transplantable interstitioma testis induced with lead acetate. Arch. Immunol. Therap. Exp. 20: 243–256, 1972.

    CAS  Google Scholar 

  43. Gardner, L. U., and H. F. Heslington, Osteosarcoma from intravenous beryllium compounds in rabbits. Fed. Proc. 5, 221, 1946.

    PubMed  CAS  Google Scholar 

  44. Nash, P., Experimental production of malignant tumors by beryllium. Lancet 1: 519, 1950.

    Article  Google Scholar 

  45. Sissons, H. A., Bone sarcomas produced experimentally in the rabbit, using compounds of beryllium. Acta Unio Intern. Contra Cancrum 7: 171, 1950.

    CAS  Google Scholar 

  46. Reeves, A. L., D. Deitch, and A. J. Vorwald, Beryllium carcinogenesis. I. Inhalation exposure of rats to beryllium sulfate aerosol. Cancer Res. 27: 439–445, 1967.

    PubMed  CAS  Google Scholar 

  47. Druckrey, H., H. Hamperl, and D. Schmahl, Cancerogene wirkung von metallischen queck-silber nach intraperitonealer gabe bei ratten. Z. Krebsforsch. 61: 511–519, 1957.

    Article  PubMed  CAS  Google Scholar 

  48. Schmahl, D., and D. Steinhoff, Versuche zur krebserzeugung mit kolloidolen silberund goldosungen an ratten. Z. Krebsforsch. 63; 586–591, 1960.

    Article  CAS  Google Scholar 

  49. Furst, A., and R. T. Haro, Carcinogenicity of metal pi-complex compounds: Metallocenes. In: Abstracts of the 10th International Cancer Congress, Houston, Austin, University of Texas Press, 1970, p. 28.

    Google Scholar 

  50. Ball, R. A., G. Van Gelder, J. W. Green, Jr., and W. O. Reece, Neoplastic sequelae following subcutaneous implanation of mice with rare earth metals. Proc. Soc. Exp. Biol. Med., 135: 426–430, 1970.

    PubMed  CAS  Google Scholar 

  51. Roe, F. J. C., E. Boyland, and K. Millican, Effect of oral administration of two tin compounds to rats over prolonged periods. Food Cosmet. Toxicol. 3: 277–280, 1965.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

Copyright information

© 1980 The Humana Press Inc.

About this protocol

Cite this protocol

Costa, M. (1980). Metal Carcinogenesis In Experimental Animals. In: Metal Carcinogenesis Testing. Biological Methods. Humana Press. https://doi.org/10.1007/978-1-60327-403-6_2

Download citation

  • DOI: https://doi.org/10.1007/978-1-60327-403-6_2

  • Publisher Name: Humana Press

  • Print ISBN: 978-0-89603-017-6

  • Online ISBN: 978-1-60327-403-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics