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Compositional Analysis of the Human Microbiome in Cancer Research

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Cancer Metabolism

Part of the book series: Methods in Molecular Biology ((MIMB,volume 1928))

Abstract

Gut microbial composition has shown to be associated with obesity, diabetes mellitus, inflammatory bowel disease, colitis, autoimmune disorders, and cancer, among other diseases. Microbiome research has significantly evolved through the years and continues to advance as we develop new and better strategies to more accurately measure its composition and function. Careful selection of study design, inclusion and exclusion criteria of participants, and methodology are paramount to accurately analyze microbial structure. Here we present the most up-to-date available information on methods for gut microbial collection and analysis.

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Authors and Affiliations

  1. Robbins College of Health and Human Sciences, Baylor University, Waco, TX, USA

    Elisa Morales & K. Leigh Greathouse

  2. Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA

    Jun Chen

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  1. Elisa Morales
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  2. Jun Chen
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Correspondence to K. Leigh Greathouse .

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  1. National Cancer Institute, North Bethesda, MD, USA

    Majda Haznadar

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Morales, E., Chen, J., Greathouse, K.L. (2019). Compositional Analysis of the Human Microbiome in Cancer Research. In: Haznadar, M. (eds) Cancer Metabolism. Methods in Molecular Biology, vol 1928. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-9027-6_16

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