Abstract
Cancer is an evolutionary process. Recent advances in sequencing technologies have allowed us to investigate intratumor heterogeneity at the single nucleotide level. Here, we describe computational methods that use sequencing data to identify genetically distinct tumor subclones and reconstruct tumor evolutionary histories.
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Goh, G., McGranahan, N., Wilson, G.A. (2019). Computational Methods for Analysis of Tumor Clonality and Evolutionary History. In: Krasnitz, A. (eds) Cancer Bioinformatics. Methods in Molecular Biology, vol 1878. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-8868-6_13
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DOI: https://doi.org/10.1007/978-1-4939-8868-6_13
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