Abstract
The field of nanomaterials has been expanding rapidly into many diverse applications within the last 20 years. With this growth, there is a significant need for new method development for the detection and characterization of nanomaterials. Understanding the physical properties of nanoscale entities and their associated reaction kinetics is crucial for monitoring their effect on environmental and human health, and in their use for practical applications. Nano-impact electrochemistry is a novel development in the field of fundamental electrochemistry that provides an ultrasensitive method for analyzing physical and redox properties of nanomaterials and their derivatives. This protocol focuses on the tools required for characterizing silver nanoparticles (AgNPs) by nano-impact electrochemistry, the preparation of microelectrodes and the methodology needed for measurement of the AgNP redox activity. The fabrication of cylindrical carbon fiber as well as gold and platinum microwire electrodes is described in detail. The analysis of nano-impact electrochemistry for the characterization of redox active entities is also outlined with examples of applications.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Zhou Y-G, Rees NV, Compton RG (2011) The electrochemical detection and characterization of silver nanoparticles in aqueous solution. Angew Chem 123:4305–4307
Xiao X, Fan F-RF, Zhou J et al (2008) Current transients in single nanoparticle collision events. J Am Chem Soc 130:16669–16677
Andreescu D, Kirk KA, Narouei FH et al (2018) Electroanalytic aspects of single-entity collision methods for bioanalytical and environmental applications. ChemElectroChem 5:2920–2936
Oja SM, Robinson DA, Vitti NJ et al (2016) Observation of multipeak collision behavior during the electro-oxidation of single Ag nanoparticles. J Am Chem Soc 139:708–718
Qiu D, Wang S, Zheng Y et al (2013) One at a time: counting single-nanoparticle/electrode collisions for accurate particle sizing by overcoming the instability of gold nanoparticles under electrolytic conditions. Nanotechnology 24:505707
Sardesai NP, Andreescu D, Andreescu S (2013) Electroanalytical evaluation of antioxidant activity of cerium oxide nanoparticles by nanoparticle collisions at microelectrodes. J Am Chem Soc 135:16770–16773
Kwon SJ, Zhou H, Fan F-RF et al (2011) Stochastic electrochemistry with electrocatalytic nanoparticles at inert ultramicroelectrodes—theory and experiments. Phys Chem Chem Phys 13:5394–5402
Karimi A, Hayat A, Andreescu S (2017) Biomolecular detection at ssdna-conjugated nanoparticles by nano-impact electrochemistry. Biosens Bioelectron 87:501–507
Anahita K, Kirk KA, Silvana A (2017) Electrochemical investigation of pH-dependent activity of polyethylenimine-capped silver nanoparticles. ChemElectroChem 4:2801–2806
Hao R, Zhang B (2016) Observing electrochemical dealloying by single-nanoparticle collision. Anal Chem 88:8728–8734
Cheng W, Zhou XF, Compton RG (2013) Electrochemical sizing of organic nanoparticles. Angew Chem 125:13218–13220
Lim CS, Tan SM, Ze S et al (2015) Impact electrochemistry of layered transition metal dichalcogenides. ACS Nano 9:8474–8483
Robinson DA, Yoo JJ, Castaneda AD et al (2015) Increasing the collision rate of particle impact electroanalysis with magnetically guided Pt-decorated iron oxide nanoparticles. ACS Nano 9:7583–7595
Cheng W, Compton RG (2014) Investigation of single-drug-encapsulating liposomes using the nano-impact method. Angew Chem Int Ed 53:13928–13930
Dick JE, Hilterbrand AT, Boika A et al (2015) Electrochemical detection of a single cytomegalovirus at an ultramicroelectrode and its antibody anchoring. Proc Natl Acad Sci U S A 112:5303–5308
Castaneda AD, Robinson DA, Stevenson KJ et al (2016) Electrocatalytic amplification of DNA-modified nanoparticle collisions via enzymatic digestion. Chem Sci 7:6450–6457
Robinson DA, Liu Y, Edwards MA et al (2017) Collision dynamics during the electrooxidation of individual silver nanoparticles. J Am Chem Soc 139:16923–16931
Acknowledgments
The manuscript was edited by Enrico Ferrari and Mikhail Soloviev. This material is based upon work supported by the National Science Foundation under Grant 1610281. Any opinions, findings, and conclusions or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the National Science Foundation.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2020 Springer Science+Business Media, LLC, part of Springer Nature
About this protocol
Cite this protocol
Kirk, K.A., Luitel, T., Narouei, F.H., Andreescu, S. (2020). Nanoparticle Characterization Through Nano-Impact Electrochemistry: Tools and Methodology Development. In: Ferrari, E., Soloviev, M. (eds) Nanoparticles in Biology and Medicine. Methods in Molecular Biology, vol 2118. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-0319-2_24
Download citation
DOI: https://doi.org/10.1007/978-1-0716-0319-2_24
Published:
Publisher Name: Humana, New York, NY
Print ISBN: 978-1-0716-0318-5
Online ISBN: 978-1-0716-0319-2
eBook Packages: Springer Protocols