1. Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery

   • Seyedeh Roya Alizadeh
   • Seyedeh Mahdieh Hashemi

   Review Article 15 January 2021 Pages: 771 - 806

   

2. Tuberculosis: current scenario, drug targets, and future prospects

   • Priyanka Bose
   • Amit K. Harit
   • Sushil K. Kashaw

   Review Article 20 January 2021 Pages: 807 - 833

   

3. In vitro and in vivo biological activities of azulene derivatives with potential applications in medicine

   • Paweł Bakun
   • Beata Czarczynska-Goslinska
   • Sebastian Lijewski

   Review Article Open access 30 January 2021 Pages: 834 - 846

   

4. Repositioning of Isatin hybrids as novel anti-tubercular agents overcoming pre-existing antibiotics resistance

   • Rakesh Kumar
   • Priya Takkar

   Review Article 30 January 2021 Pages: 847 - 876

   

5. Benzopyrylium salts as new anticancer, antibacterial, and antioxidant agents

   • Swayamsiddha Kar
   • Abdul Akhir
   • Nageswara Rao Golakoti

   Original Research 13 January 2021 Pages: 877 - 885

   

6. Anti-inflammatory scalarane-type sesterterpenes, erectascalaranes A–B, from the marine sponge Hyrtios erectus attenuate pro-inflammatory cyclooxygenase-2 and 5-lipoxygenase

   • Prima Francis
   • Kajal Chakraborty

   Original Research 15 January 2021 Pages: 886 - 896

   

7. Novel 1-methoxyindole- and 2-alkoxyindole-based chalcones: design, synthesis, characterization, antiproliferative activity and DNA, BSA binding interactions

   • Zuzana Kudličková
   • Peter Takáč
   • Ján Mojžiš

   Original Research 16 January 2021 Pages: 897 - 912

   

8. γ- and δ-lactones as fumarate esters analogues and their neuroprotective effects

   • Francesca Cateni
   • Patrizia Nitti
   • Maurizio Romano

   Original Research 16 January 2021 Pages: 913 - 924

   

9. Synthesis and in vitro evaluation of triphenylphosphonium derivatives of acetylsalicylic and salicylic acids: structure-dependent interactions with cancer cells, bacteria, and mitochondria

   • Olga V. Tsepaeva
   • Taliya I. Salikhova
   • Vladimir F. Mironov

   Original Research 21 January 2021 Pages: 925 - 939

   

10. Pentacyclic triterpene acid conjugated with mitochondria-targeting cation F16: Synthesis and evaluation of cytotoxic activities

    • Anna Yu. Spivak
    • Darya A. Nedopekina
    • Usein M. Dzhemilev

    Original Research 25 January 2021 Pages: 940 - 951

    

11. Isonicotinoyl hydrazones of pyridoxine derivatives: synthesis and antimycobacterial activity

    • Nikita V. Shtyrlin
    • Rail M. Khaziev
    • Yurii G. Shtyrlin

    Original Research 01 February 2021 Pages: 952 - 963

    

12. Phthalamide derivatives as ACE/AChE/BuChE inhibitors against cardiac hypertrophy: an in silico, in vitro, and in vivo modeling approach

    • Erik Andrade-Jorge
    • Jessica E. Rodríguez
    • Rafael Villalobos-Molina

    Original Research 03 February 2021 Pages: 964 - 976

    

13. Evaluation of 3-carbamoylpropanoic acid analogs as inhibitors of human hypoxia-inducible factor (HIF) prolyl hydroxylase domain enzymes

    • MuiPhin Chong
    • LeeRoy Toh
    • KarKheng Yeoh

    Original Research 03 February 2021 Pages: 977 - 986

    

14. Synthesis, characterization, crystal structures, and anticancer activity of some new 2,3-dihydro-1,5-benzoxazepines

    • Felix Odame
    • Recardia Schoeman
    • Carminita Frost

    Original Research 11 February 2021 Pages: 987 - 1004

    

15. Phenylpropanoids from Liparis nervosa and their in vitro antioxidant and α-glucosidase inhibitory activities

    • Liang Liu
    • Meijia Zou
    • Xianwen Zhang

    Original Research 12 February 2021 Pages: 1005 - 1010