Volume 29, Issue 7

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July 2020

Special Issue in Honor of Professor Robert P. Hanzlik on the Occasion of His Retirement

Issue Editors:

Binghe Wang,
Siming L. Wang

17 articles in this issue

In honor of Professor Robert P. Hanzlik on the occasion of his retirement
Siming L. Wang
Longqin Hu
Binghe Wang
Editorial 19 June 2020 Pages: 1091 - 1092
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Drug–protein adducts: past, present, and future
Thomas A. Baillie
Review Article 27 May 2020 Pages: 1093 - 1104
Part of 2 collections:

Special Issue in Honor of Professor Robert P. Hanzlik

Drug Design reviews
Anticancer strategies by upregulating p53 through inhibition of its ubiquitination by MDM2
Abiodun Anifowose
Ayodeji A. Agbowuro
Binghe Wang
Review Article 06 June 2020 Pages: 1105 - 1121
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Substrate-based chemical probes for Alzheimer’s γ-secretase
Michael S. Wolfe
Review Article 31 May 2020 Pages: 1122 - 1132
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Rheostat positions: A new classification of protein positions relevant to pharmacogenomics
Aron W. Fenton
Braelyn M. Page
Liskin Swint-Kruse
Review Article 07 June 2020 Pages: 1133 - 1146
Part of 2 collections:

Special Issue in Honor of Professor Robert P. Hanzlik

Drug Design reviews
PAWI-2: A novel inhibitor for eradication of cancer
Jiongjia Cheng
John R. Cashman
Review Article 06 June 2020 Pages: 1147 - 1159
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Template-based alignment modeling: an innovative ligand-based approach for medicinal chemists
Zhijun Wu
Spencer Knapp
Victor Hruby
Review Article 27 May 2020 Pages: 1160 - 1167
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
A comprehensive review of ethnopharmacological uses, phytochemistry, biological activities, and future prospects of Nigella glandulifera
Yunliang Zheng
Qiao Zhang
Xingjiang Hu
Review Article 22 May 2020 Pages: 1168 - 1186
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Discovery of sultam-containing small-molecule disruptors of the huntingtin–calmodulin protein–protein interaction
Nicholas J. Klus
Khushboo Kapadia
Jeffrey Aubé
Original Research 12 June 2020 Pages: 1187 - 1198
Part of 2 collections:

Special Issue in Honor of Professor Robert P. Hanzlik

Protein-protein interactions
Inducing apoptosis through upregulation of p53: structure–activity exploration of anthraquinone analogs
Abiodun Anifowose
Ayodeji A. Agbowuro
Binghe Wang
Original Research 07 June 2020 Pages: 1199 - 1210
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Compound collections at KU 1947–2017: cheminformatic analysis and computational protein target prediction
Zachary Pearson
Manvendra Singh
Zarko Boskovic
Original Research 03 June 2020 Pages: 1211 - 1222
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers
Anand H. Shinde
Someshwar Nagamalla
Shyam Sathyamoorthi
Original Research 17 May 2020 Pages: 1223 - 1229
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Bergaptol, a mechanism-based inactivator of CYP2C9
Tingting Jiang
Ting Cheng
Jiang Zheng
Original Research 26 May 2020 Pages: 1230 - 1237
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Screening trimethoprim primary metabolites for covalent binding to albumin
Whitney M. Nolte
Robert T. Tessman
Jennifer L. Goldman
Original Research 04 June 2020 Pages: 1238 - 1246
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity
Jian Jin
Banrida Wahlang
Russell A. Prough
Original Research 07 June 2020 Pages: 1247 - 1263
Part of 1 collection:

Special Issue in Honor of Professor Robert P. Hanzlik
Synthesis and evaluation of new 4-peptidamido-2-fluorobenzyl phosphoramide mustard conjugates as prodrugs activated by prostate-specific antigen
Herve Aloysius
Longqin Hu
Original Research 03 June 2020 Pages: 1264 - 1279
Part of 2 collections:

Special Issue in Honor of Professor Robert P. Hanzlik

Prodrugs
Synthesis and evaluation of new peptide-linked doxorubicin conjugates as prodrugs activated by prostate-specific antigen
Herve Aloysius
Longqin Hu
Original Research 04 June 2020 Pages: 1280 - 1299
Part of 2 collections:

Special Issue in Honor of Professor Robert P. Hanzlik

Prodrugs

Volume 29, Issue 7

In honor of Professor Robert P. Hanzlik on the occasion of his retirement

Drug–protein adducts: past, present, and future

Anticancer strategies by upregulating p53 through inhibition of its ubiquitination by MDM2

Substrate-based chemical probes for Alzheimer’s γ-secretase

Rheostat positions: A new classification of protein positions relevant to pharmacogenomics

PAWI-2: A novel inhibitor for eradication of cancer

Template-based alignment modeling: an innovative ligand-based approach for medicinal chemists

A comprehensive review of ethnopharmacological uses, phytochemistry, biological activities, and future prospects of Nigella glandulifera

Discovery of sultam-containing small-molecule disruptors of the huntingtin–calmodulin protein–protein interaction

Inducing apoptosis through upregulation of p53: structure–activity exploration of anthraquinone analogs

Compound collections at KU 1947–2017: cheminformatic analysis and computational protein target prediction

N-arylated oxathiazinane heterocycles are convenient synthons for 1,3-amino ethers and 1,3-amino thioethers

Bergaptol, a mechanism-based inactivator of CYP2C9

Screening trimethoprim primary metabolites for covalent binding to albumin

Dioxin-like and non-dioxin-like PCBs differentially regulate the hepatic proteome and modify diet-induced nonalcoholic fatty liver disease severity

Synthesis and evaluation of new 4-peptidamido-2-fluorobenzyl phosphoramide mustard conjugates as prodrugs activated by prostate-specific antigen

Synthesis and evaluation of new peptide-linked doxorubicin conjugates as prodrugs activated by prostate-specific antigen

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