Design, synthesis, and in vitro evaluation of novel 1,3,4-oxadiazolecarbamothioate derivatives of Rivastigmine as selective inhibitors of BuChE Akram FallahFarajollah MohanazadehMaliheh Safavi Original Research 16 December 2019 Pages: 341 - 355
Discovery of a nanomolar glyoxalase-I inhibitor using integrated ligand-based pharmacophore modeling and molecular docking Nizar A. Al-Shar’iEnas K. Al-RousanMohammad A. Hassan Original Research 13 December 2019 Pages: 356 - 376
Styrylcoumarin 7-SC2 induces apoptosis in SW480 human colon adenocarcinoma cells and inhibits azoxymethane-induced aberrant crypt foci formation in BALB/c mice Angie Herrera-RTonny W. NaranjoWilson Cardona-G Original Research 09 December 2019 Pages: 377 - 395
Design, synthesis, and bioevaluation of novel oxoindolin-2-one derivatives incorporating 1-benzyl-1H-1,2,3-triazole Ta Thu LanDuong Tien AnhNguyen-Hai Nam Original Research 25 December 2019 Pages: 396 - 408
Synthesis, cytotoxicity, and antitubercular studies of novel thiophene containing 2-methyl-3-methyl/ethyl acrylates from Baylis–Hillman adducts Neelaiah Babu G.Abi TadesseVijai Basker G. Original Research 12 December 2019 Pages: 409 - 416
Antimycotic sensitivity evaluation against Candida ATCC species of 1,2,3-triazoles derived from 5-chloro-2(2,4-dichlorophenoxy)phenol Cristian A. Pastrana-GómezCarmen Cecilia Almonacid-UrregoErick Cuevas-Yáñez Original Research 17 December 2019 Pages: 417 - 425
Hostaflavanol A, a new anti-inflammatory and antioxidant activities flavanol from the flowers of Hosta plantaginea Li YangYi-min LinJun-wei He Original Research 14 December 2019 Pages: 426 - 430
Synthesis, in vitro antigiardial activity, SAR analysis and docking study of substituted chalcones David Cáceres-CastilloRubén M. CarballoGonzalo J. Mena-Rejón Original Research 27 December 2019 Pages: 431 - 441
Design, synthesis and biological evaluation of novel N,4-diphenylthiazol-2-amine derivatives AfraQuasar A. NadafDelicia A. BarrettoImtiyaz Ahmed M. Khazi Original Research 30 December 2019 Pages: 442 - 458
Synthesis and biological activity of fibrate-based acyl- and alkyl-phenoxyacetic methyl esters and 1,2-dihydroquinolines Abraham PuchetaAarón MendietaJoaquín Tamariz Original Research 26 January 2020 Pages: 459 - 478
Curcumin analogs: synthesis and biological activities Mahmood Khudhayer OglahYasser Fakri Mustafa Original Research 30 December 2019 Pages: 479 - 486
Naphthoquinones isolated from Eleutherine plicata herb: in vitro antimalarial activity and molecular modeling to investigate their binding modes Valdicley Vieira ValeJorddy Neves CruzMaria Fani Dolabela Original Research 18 January 2020 Pages: 487 - 494
Synthesis, biological activities, and 3D-QSAR studies of (R)-2-phenyl-4,5-dihydrothiazole-4-carboxamide derivatives containing a sulfonohydrazide moiety Jingbo LiuFengyun LiZhengming Li Original Research 15 January 2020 Pages: 495 - 503
Binding mechanism, conformation, and stability of diflunisal and mycophenolic acid with p300 HAT enzyme using molecular dynamics simulation and binding free energy analysis Sivanandam MagudeeswaranKumaradhas Poomani Original Research 14 January 2020 Pages: 504 - 518
A conjugated mTOR/MEK bifunctional inhibitor as potential polypharmacological anticancer agent: the prototype compound discovery Qiangqiang TaoFang FangHao Wang Original Research 13 January 2020 Pages: 519 - 527
Synthesis, anticancer evaluation, and molecular docking studies of benzoxazole linked combretastatin analogues Vukoti Kiran KumarVenkat Swamy PuliK. R. S. Prasad Original Research 18 January 2020 Pages: 528 - 537
Design, synthesis, and characterization of novel substituted 1,2,4-oxadiazole and their biological broadcast Paranjay H. ParikhJignesh B. TimaniyaKaushal P. Patel Original Research 18 January 2020 Pages: 538 - 548
Potential neurotrophic activity and cytotoxicity of selected C21 steroidal glycosides from Cynanchum otophyllum Jinrun DongGrace Gar-Lee YueMinghua Qiu Original Research 17 January 2020 Pages: 549 - 555
Repositioning of fluoxetine and paroxetine: study of potential antibacterial activity and its combination with ciprofloxacin Vitória S. FolettoMarissa B. SerafinRosmari Hörner Original Research 18 January 2020 Pages: 556 - 563
Synthesis and evaluation of chromone-2-carboxamido-alkylamines as potent acetylcholinesterase inhibitors Paptawan SuwanhomTeerapat NualnoiLuelak Lomlim Original Research 21 January 2020 Pages: 564 - 574