Design, synthesis and anti-cancer evaluation of novel podophyllotoxin derivatives as potent tubulin-targeting agents Cui HuXiang ZhuYong-Hua Yang Original Research 11 December 2017 Pages: 351 - 365
Tonifying qi and Warming yang, a compound traditional Chinese herbal medicine, suppresses AngII-induced cardiac H9c2 cells apoptosis through regulating PI3K/Akt signaling pathway Guoliang ZouWeili ZhongLi Liu Original Research 23 October 2017 Pages: 366 - 373
Design, synthesis and biological evaluation of phenylpicolinamide sorafenib derivatives as antitumor agents Chunjiang WuShan XuPengwu Zheng Original Research 20 September 2017 Pages: 374 - 387
Antiplatelet activity, molecular docking and QSAR study of novel N′-arylmethylidene-3-methyl-1-phenyl-6-p-chlorophenyl-1H-pyrazolo[3,4-b] pyridine-4-carbohydrazides Ayesha RamzanSara SiddiquiMuhammad Asim Raza Basra Original Research 20 September 2017 Pages: 388 - 405
Sealed tube promoted coupling of camptothecin and norcantharidin acid ester and their preliminary biological activity evaluation in vitro Xian H. WangFu H. YangChan Li Original Research 21 September 2017 Pages: 406 - 411
Synthesis and cytotoxicity of pyrido[4,3-b]carbazole alkaloids against HCT-116 and HL-60 cells Tomoki ItohNoriyuki HataeMinoru Ishikura Original Research 27 September 2017 Pages: 412 - 419
QSAR studies of indoyl aryl sulfides and sulfones as reverse transcriptase inhibitors Pablo R. DuchowiczDaniel E. BaceloGustavo P. Romanelli Original Research 23 September 2017 Pages: 420 - 428
Synthesis, biological evaluation, molecular docking, and ADMET studies of some isoxazole-based amides Sushama KauthaleSunil TekaleRajendra Pawar Original Research 03 October 2017 Pages: 429 - 441
1,4-Disubstituted-5-hydroxy-3-methylpyrazoles and some derived ring systems as cytotoxic and DNA binding agents. Synthesis, in vitro biological evaluation and in silico ADME study Mona Hany BadrHeba Attia Abd El Razik Original Research 21 September 2017 Pages: 442 - 457
Convenient synthesis, antimalarial and antimicrobial potential of thioethereal 1,4-disubstituted 1,2,3-triazoles with ester functionality C. P. KaushikAshima Pahwa Original Research 06 October 2017 Pages: 458 - 469
A new benzofuran derivative glycoside and a new coumarin glycoside from roots of Heracleum dissectum Ledeb Jie MiYajie PengHailong Zhang Original Research 20 September 2017 Pages: 470 - 475
Exploring sulfonate esters of 5-arylidene thiazolidine-2,4-diones as PTP1B inhibitors with anti-hyperglycemic activity Manoj Kumar MahapatraRajnish KumarManoj Kumar Original Research 26 September 2017 Pages: 476 - 487
Design, synthesis and biological evaluation of 4-methoxy diaryl isophthalates as antiplatelet agents Liu Xiu-jieWang Chao-qingLiu Xu-guang Original Research 26 September 2017 Pages: 488 - 496
Synthesis and antiprotozoal activity of furanchalcone–quinoline, furanchalcone–chromone and furanchalcone–imidazole hybrids Elisa GarcíaJuan C. CoaWilson I. Cardona Original Research 26 September 2017 Pages: 497 - 511
Synthesis and antiviral study of 4-(7,7-dimethyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazolin-2-yl) morpholine derivatives Balaraman SelvakumarNaveen GujjarKuppanagounder P. Elango Original Research 25 September 2017 Pages: 512 - 519
Design, synthesis and biological evaluation of 2-Phenyl-4H-chromen-4-one derivatives as polyfunctional compounds against Alzheimer’s disease Manjinder SinghManinder KaurOm Silakari Original Research 03 October 2017 Pages: 520 - 530
Investigating the role of miRNA-98 and miRNA-214 in chemoresistance of HepG2/Dox cells: studying their effects on predicted ABC transporters targets Ahmed R. HamedMohamed EmaraGhada H. Elsayed Original Research 27 September 2017 Pages: 531 - 537
In vitro anticholinesterase activity and molecular docking studies of coumarin derivatives isolated from roots of Heptaptera cilicica Hilal ÖzbekZühal GüvenalpÖmür L. Demirezer Original Research 22 September 2017 Pages: 538 - 545
Design, synthesis, molecular modeling, and ADMET studies of some pyrazoline derivatives as shikimate kinase inhibitors Jainey P. JamesK. Ishwar BhatShrinivas D. Joshi Original Research 10 November 2017 Pages: 546 - 559
Design, synthesis and cytotoxicity evaluation of pyrazolyl pyrazoline and pyrazolyl aminopyrimidine derivatives as potential anticancer agents Raquib AlamAftab AlamRahisuddin Original Research 06 October 2017 Pages: 560 - 570
New series of 4(3H)-quinazolinone derivatives: syntheses and evaluation of antitumor and antiviral activities Samir Y. AbbasKhairy A. M. El-BayoukiEslam A. Mostafa Original Research 05 October 2017 Pages: 571 - 582
Enzymic synthesis and biological evaluation of injectable glutathione-everolimus Haibo WangXiaohe ZhengTianmin Zhu Original Research 23 November 2017 Pages: 583 - 591
Imidazole-thiazole coupled derivatives as novel lanosterol 14-α demethylase inhibitors: ionic liquid mediated synthesis, biological evaluation and molecular docking study Anna Pratima G. NikaljeShailee V. TiwariKshipra S. Karnik Original Research 29 October 2017 Pages: 592 - 606
Understanding of the conformational flexibility and electrostatic properties of coumarin derivatives in the active site of S. cerevisiae α-glucosidase Y. J. QiH. N. LuJ. Q. Dong Original Research 10 October 2017 Pages: 607 - 617
The uses of cyclohexan-1,4-dione for the synthesis of thiophene derivatives as new anti-proliferative, prostate anticancer, c-Met and tyrosine kinase inhibitors Rafat M. MoharebFatima Al-OmranRehab A. Ibrahim Original Research 05 October 2017 Pages: 618 - 633
Synthesis of novel acridine-sulfonamide hybrid compounds as acetylcholinesterase inhibitor for the treatment of alzheimer’s disease Ramazan Ulusİbrahim EsirdenMuharrem Kaya Original Research 13 October 2017 Pages: 634 - 641
Synthesis and anticonvulsant activity of some novel 7-(benzylamino) -1H-benzo[b][1,4]diazepine-2,4(3H, 5H)-dione derivatives Yun-Peng ShaoRong-Bi HanFeng-Yu Piao Original Research 14 October 2017 Pages: 642 - 652
Newer series of trioxane derivatives as potent antimalarial agents Mithun RudrapalZartaj Washmin BanuDipak Chetia Original Research 03 October 2017 Pages: 653 - 668
Metabolomics and genomics: revealing the mechanism of corydalis alkaloid on anti-inflammation in vivo and in vitro Yan WangTianjiao LiTao Bo Original Research 30 October 2017 Pages: 669 - 678
Synthesis and phospholipidosis effect of a series of cationic amphiphilic compounds: a case study to evaluate in silico and in vitro assays Susan LepriAurora ValeriLaura Goracci Original Research 25 October 2017 Pages: 679 - 692
Correction to: Isolation, characterization and antiproliferative evaluation of constituents from stem extracts of Alafia barteri Oliv. Hook. F. Abdulmumeen A. HamidOlapeju O. AiyelaagbeArvind S. Negi Author Correction 26 December 2017 Pages: 693 - 693
