1. Hydrazide–hydrazones as potential antimicrobial agents: overview of the literature since 2010

   • Łukasz Popiołek

   Review Article Open access 25 November 2016 Pages: 287 - 301

   

2. Halogenated 2-amino-4H-pyrano[3,2-h]quinoline-3-carbonitriles as antitumor agents and structure–activity relationships of the 4-, 6-, and 9-positions

   • Ahmed M. Fouda

   Original Research 19 November 2016 Pages: 302 - 313

3. Pharmacoinformatics and molecular docking studies reveal potential novel Proline Dehydrogenase (PRODH) compounds for Schizophrenia inhibition

   • Sheikh Arslan Sehgal

   Original Research 19 November 2016 Pages: 314 - 326

   

4. Identification of novel inhibitors of HCV NS3 protease genotype 3 subtype B through molecular docking studies of phytochemicals from Boerhavia diffusa L

   • G. R. JunaBeegum
   • Amjesh Revikumar
   • Vetha Sundaram Sugunan

   Original Research 22 November 2016 Pages: 327 - 334

   

5. Antidiabetic activity and histopathological analysis of carnosol isolated from Artemisia indica linn in streptozotocin-induced diabetic rats

   • Imran Khan
   • Waqar Ahmad
   • Abeer Abdelhalim

   Original Research 23 November 2016 Pages: 335 - 343

   

6. Probing the structural requirements for thyroid hormone receptor inhibitory activity of sulfonylnitrophenylthiazoles (SNPTs) using 2D-QSAR and 3D-QSAR approaches

   • Fang-Fang Wang
   • Wei Yang
   • Guo-Wei Le

   Original Research 23 November 2016 Pages: 344 - 360

   

7. Combined 3D-QSAR modeling and molecular docking study on spiro-derivatives as inhibitors of acetyl-CoA carboxylase

   • Jian Gao
   • Jie Sun
   • Tonghui Huang

   Original Research 25 November 2016 Pages: 361 - 371

   

8. Steroidal imidazoles: Synthesis, characterization, molecular docking studies with DNA and in vitro cytotoxicity

   • Ayaz Mahmood Dar
   • Shams Uzzaman
   • Yusuf Khan

   Original Research 26 November 2016 Pages: 372 - 383

   

9. The toxicity and DNA-damage mechanism of α-Fe₂O₃ nanoparticles

   • Xiaoxing Wang
   • Yan Gu
   • Yingping Huang

   Original Research 02 December 2016 Pages: 384 - 389

   

10. Computational investigation on inhibition mechanism of BRAF^V600E by Vemurafenib (PLX4032) and its analogue PLX4720

    • XiaoYun Wu
    • Yu Fu
    • JiaJie Zhang

    Original Research 12 December 2016 Pages: 390 - 396

    

11. Cytotoxic and cancer preventive activity of benzotrithioles and benzotrithiole oxides, synthetic analogues of varacins

    • Alexandra S. Kuzmich
    • Tatyana M. Khomenko
    • Nariman F. Salakhutdinov

    Original Research 16 December 2016 Pages: 397 - 404

    

12. Interaction mechanism of pepsin with a natural inhibitor gastrodin studied by spectroscopic methods and molecular docking

    • Jie Wang
    • Calvin Chan
    • Zhen-dan He

    Original Research 16 December 2016 Pages: 405 - 413

    

13. Inhibitors of multidrug efflux pumps of Pseudomonas aeruginosa from natural sources: An in silico high-throughput virtual screening and in vitro validation

    • Gianmarco Mangiaterra
    • Emiliano Laudadio
    • Roberta Galeazzi

    Original Research 19 December 2016 Pages: 414 - 430

    

14. Synthesis and antimicrobial activity of pyrimidinyl bis(benzazoles)

    • Dandu Seenaiah
    • Tamatam Rekha
    • Venkatapuram Padmavathi

    Original Research 21 December 2016 Pages: 431 - 441

    

15. Antimicrobial mechanism of the major active essential oil compounds and their structure–activity relationship

    • Xian Hui
    • Ge Yan
    • Wen-Yun Gao

    Original Research 27 December 2016 Pages: 442 - 449

    

16. Computational evaluation of glutamine synthetase as drug target against infectious diseases: molecular modeling, substrate-binding analysis, and molecular dynamics simulation studies

    • Nidhi Singh
    • Mohammad Imran Siddiqi

    Original Research 27 December 2016 Pages: 450 - 460

    

17. Novel polyfunctional esters of ibuprofen and ketoprofen with hypolipidemic, lipoxygenase inhibitory and enhanced anti-inflammatory activity

    • Panagiotis Theodosis-Nobelos
    • Paraskevi Tziona
    • Eleni A. Rekka

    Original Research 27 December 2016 Pages: 461 - 472

18. Synthesis of an organo-ruthenium aminoquinoline-trioxane hybrid and evaluation of its activity against Plasmodium falciparum and its toxicity toward normal mammalian cells

    • Alberto Martínez
    • Christiane Deregnaucourt
    • Roberto A. Sánchez-Delgado

    Original Research 30 December 2016 Pages: 473 - 483

    

19. Microwave synthesis, biological evaluation and docking studies of 2-substituted methyl 1-(4-fluorophenyl)-1H-benzimidazole-5-carboxylates

    • Suhas A. Shintre
    • Deresh Ramjugernath
    • Neil A. Koorbanally

    Original Research 05 January 2017 Pages: 484 - 498

    

20. Geniposide and geniposidic acid, modified forms of genipin, attenuate genipin-induced mitochondrial apoptosis without altering the anti-inflammatory ability in KGN cell line

    • Tao Zuo
    • Wenming Xu
    • Minghui Zhu

    Original Research 05 January 2017 Pages: 499 - 508