Volume 24, Issue 7

Search all Medicinal Chemistry Research articles

July 2015

31 articles in this issue

Recent advances and therapeutic journey of coumarins: current status and perspectives
Kuldipsinh P. Barot
Shailesh V. Jain
Manjunath D. Ghate
Review Article 11 March 2015 Pages: 2771 - 2798
Semisynthetic hybrids of boswellic acids: a novel class of potential anti-inflammatory and anti-arthritic agents
Devdutt Chaturvedi
Parmesh Kumar Dwivedi
Virendra Mishra
Original Research 10 February 2015 Pages: 2799 - 2812
Synthesis and biological evaluation of new 1,2,4-triazole derivatives with their potentiometric titrations
Ozlem Aktas-Yokus
Haydar Yuksek
Sengul Alpay-Karaoglu
Original Research 10 February 2015 Pages: 2813 - 2824
Synthesis, toxicity and chemo-sensitization of HeLa cells to etoposide, of some 2-methyl amino acid ester-substituted-1,3-benzoxazines
Saleh K. Ihmaid
Cheree Fitzgibbon
Jasim M. A. Al-Rawi
Original Research 13 February 2015 Pages: 2825 - 2837
Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines
Brian D. Wright
Michael C. Deblock
Wiley J. Youngs
Original Research 13 February 2015 Pages: 2838 - 2861
Synthesis of some pyrazolylaldehyde N-isonicotinoyl hydrazones and 2,5-disubstituted 1,3,4-oxadiazoles as DNA photocleaving agents
M. Kumar
V. Kumar
V. Beniwal
Original Research 19 February 2015 Pages: 2862 - 2870
Synthesis of costunolide derivatives by Pd-catalyzed Heck arylation and evaluation of their cytotoxic activities
P. R. Rao Vadaparthi
Ch. Pavan Kumar
K. Suresh Babu
Original Research 19 February 2015 Pages: 2871 - 2878
C ²,N-dimethylbenzylamine cyclopalladated compounds: evaluation of cytotoxic, mutagenic and antitubercular activities
Antonio Carlos Moro
Gislaine Aparecida da Cunha
Clarice Queico Fujimura Leite
Original Research 24 February 2015 Pages: 2879 - 2888
Immunomodulatory activity of kaempferol 5-O-β-d-glucopyranoside from Indigofera aspalathoides Vahl ex DC. (Papilionaceae)
Subramaniam Swarnalatha
Appavoo Umamaheswari
Ayarivan Puratchikody
Original Research 24 February 2015 Pages: 2889 - 2897
Two homoisoflavonoids act as peroxisome proliferator-activated receptor agonists
Hsiang-Ru Lin
Original Research 27 February 2015 Pages: 2898 - 2905
Design, synthesis and antiproliferative evaluation of some B-homo steroidal lactams
Jianguo Cui
Qifu Lin
Erbin Kong
Original Research 27 February 2015 Pages: 2906 - 2915
New antimicrobial and cytotoxic acylated triterpenoidal saponins from Gleditsia aquatica
Ehab A. Ragab
Original Research 28 February 2015 Pages: 2916 - 2925
Synthesis and activity of (+)-usnic acid and (−)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis
Olga B. Bekker
Dmitry N. Sokolov
Valery. N. Danilenko
Original Research 01 March 2015 Pages: 2926 - 2938
Chemical constituents from Chorisia chodatii flowers and their biological activities
John Refaat
Mamdouh N. Samy
Mohamed S. Kamel
Original Research 04 March 2015 Pages: 2939 - 2949
Design and synthesis of 5-chloro-2-hydroxy-3-triazolylbenzoic acids as HIV integrase inhibitors
Jie Chen
Cheng-Fu Liu
Li-Ming Hu
Original Research 05 March 2015 Pages: 2950 - 2959
Discovery of Rimonabant and its potential analogues as anti-TB drug candidates
J. M. Gajbhiye
N. A. More
V. H. Masand
Original Research 07 March 2015 Pages: 2960 - 2971
Molecular dynamics simulated validation of anti-cancerous alkaloids as Topo IIβ inhibitors screened by QSAR, pharmacophore and molecular docking approaches
Swati Singh
Manika Awasthi
Upendra N. Dwivedi
Original Research 08 March 2015 Pages: 2972 - 2985
Novel lead generation of an anti-tuberculosis agent active against non-replicating mycobacteria: exploring hybridization of pyrazinamide with multiple fragments
Shankar D. Markad
Parvinder Kaur
Pravin S. Iyer
Original Research 08 March 2015 Pages: 2986 - 2992
Design, synthesis, molecular modeling and anti-breast cancer activity of novel quinazolin-4-one derivatives linked to thiazolidinone, oxadiazole or pyrazole moieties
Marwa F. Ahmed
Amany Belal
Mahmoud Youns
Original Research 08 March 2015 Pages: 2993 - 3007
Identification of 3-hydroxy-4[3,4-dihydro-3-oxo-2H-1,4-benzoxazin-4-yl]-2,2-dimethyldihydro-2H-benzopyran derivatives as potassium channel activators and anti-inflammatory agents
Mohsina Bano
Kuldipsinh P. Barot
Manjunath D. Ghate
Original Research 10 March 2015 Pages: 3008 - 3020
Syntheses, crystal structures, in vitro antitumor and free radical scavenging activity evaluation of a series of 2-substituted thiophenes
Yara E. El-Shorafa
Daisy H. Fleita
Rafat M. Mohareb
Original Research 10 March 2015 Pages: 3021 - 3036
QSAR study of VEGFR-2 inhibitors by using genetic algorithm-multiple linear regressions (GA-MLR) and genetic algorithm-support vector machine (GA-SVM): a comparative approach
Mehdi Nekoei
Majid Mohammadhosseini
Eslam Pourbasheer
Original Research 10 March 2015 Pages: 3037 - 3046
Synthesis and anticonvulsant activity of new N-phenyl-2-(4-phenylpiperazin-1-yl)acetamide derivatives
Krzysztof Kamiński
Beata Wiklik
Jolanta Obniska
Original Research Open access 10 March 2015 Pages: 3047 - 3061
4D-QSAR studies of coumarin derivatives as HIV-1 integrase 3′-processing inhibitors
Rajesh B. Patil
Sanjay D. Sawant
Original Research 14 March 2015 Pages: 3062 - 3076
Synthesis of phenyl thiazole hydrazones and their activity against glycation of proteins
Khalid Mohammed Khan
Muhammad Irfan
M. Iqbal Choudhary
Original Research 15 March 2015 Pages: 3077 - 3085
Design and synthesis of new antidiabetic α-glucosidase and α-amylase inhibitors based on pyrimidine-fused heterocycles
Sara Shahidpour
Farhad Panahi
Ali Khalafi-Nezhad
Original Research 15 March 2015 Pages: 3086 - 3096
Theoretical design of new indole-3-carboxamide derivatives as renin inhibitors
Estella G. da Mota
Mariene H. Duarte
Matheus P. Freitas
Original Research 22 March 2015 Pages: 3097 - 3106
Synthesis and anticancer activity of thiosubstituted purines
Alicja Kowalska
Małgorzata Latocha
Krystian Pluta
Original Research Open access 25 March 2015 Pages: 3107 - 3116
Click chemistry inspired synthesis of piperazine-triazole derivatives and evaluation of their antimicrobial activities
Poonam Khedar
Kasiviswanadharaju Pericherla
Anil Kumar
Original Research 27 March 2015 Pages: 3117 - 3126
Erratum to: A benzimidazopyridoquinoxaline as promising scaffold for G-quadruplex DNA targeting
Asmae Zanzoul
Youssef Ramli
Geneviève Pratviel
Erratum 29 March 2015 Pages: 3127 - 3127
RETRACTED ARTICLE: Functionalized benzyls as selective κ-OR agonists
Bojidarka Ivanova
Michael Spiteller
Original Research 01 June 2014 Pages: 3128 - 3128

Volume 24, Issue 7

Recent advances and therapeutic journey of coumarins: current status and perspectives

Semisynthetic hybrids of boswellic acids: a novel class of potential anti-inflammatory and anti-arthritic agents

Synthesis and biological evaluation of new 1,2,4-triazole derivatives with their potentiometric titrations

Synthesis, toxicity and chemo-sensitization of HeLa cells to etoposide, of some 2-methyl amino acid ester-substituted-1,3-benzoxazines

Anti-tumor activity of lipophilic imidazolium salts on select NSCLC cell lines

Synthesis of some pyrazolylaldehyde N-isonicotinoyl hydrazones and 2,5-disubstituted 1,3,4-oxadiazoles as DNA photocleaving agents

Synthesis of costunolide derivatives by Pd-catalyzed Heck arylation and evaluation of their cytotoxic activities

C ²,N-dimethylbenzylamine cyclopalladated compounds: evaluation of cytotoxic, mutagenic and antitubercular activities

Immunomodulatory activity of kaempferol 5-O-β-d-glucopyranoside from Indigofera aspalathoides Vahl ex DC. (Papilionaceae)

Two homoisoflavonoids act as peroxisome proliferator-activated receptor agonists

Design, synthesis and antiproliferative evaluation of some B-homo steroidal lactams

New antimicrobial and cytotoxic acylated triterpenoidal saponins from Gleditsia aquatica

Synthesis and activity of (+)-usnic acid and (−)-usnic acid derivatives containing 1,3-thiazole cycle against Mycobacterium tuberculosis

Chemical constituents from Chorisia chodatii flowers and their biological activities

Design and synthesis of 5-chloro-2-hydroxy-3-triazolylbenzoic acids as HIV integrase inhibitors

Discovery of Rimonabant and its potential analogues as anti-TB drug candidates

Molecular dynamics simulated validation of anti-cancerous alkaloids as Topo IIβ inhibitors screened by QSAR, pharmacophore and molecular docking approaches

Novel lead generation of an anti-tuberculosis agent active against non-replicating mycobacteria: exploring hybridization of pyrazinamide with multiple fragments

Design, synthesis, molecular modeling and anti-breast cancer activity of novel quinazolin-4-one derivatives linked to thiazolidinone, oxadiazole or pyrazole moieties

Identification of 3-hydroxy-4[3,4-dihydro-3-oxo-2H-1,4-benzoxazin-4-yl]-2,2-dimethyldihydro-2H-benzopyran derivatives as potassium channel activators and anti-inflammatory agents

Syntheses, crystal structures, in vitro antitumor and free radical scavenging activity evaluation of a series of 2-substituted thiophenes

QSAR study of VEGFR-2 inhibitors by using genetic algorithm-multiple linear regressions (GA-MLR) and genetic algorithm-support vector machine (GA-SVM): a comparative approach

Synthesis and anticonvulsant activity of new N-phenyl-2-(4-phenylpiperazin-1-yl)acetamide derivatives

4D-QSAR studies of coumarin derivatives as HIV-1 integrase 3′-processing inhibitors

Synthesis of phenyl thiazole hydrazones and their activity against glycation of proteins

Design and synthesis of new antidiabetic α-glucosidase and α-amylase inhibitors based on pyrimidine-fused heterocycles

Theoretical design of new indole-3-carboxamide derivatives as renin inhibitors

Synthesis and anticancer activity of thiosubstituted purines

Click chemistry inspired synthesis of piperazine-triazole derivatives and evaluation of their antimicrobial activities

Erratum to: A benzimidazopyridoquinoxaline as promising scaffold for G-quadruplex DNA targeting

RETRACTED ARTICLE: Functionalized benzyls as selective κ-OR agonists

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