A comprehensive review on bioactive fused heterocycles as purine-utilizing enzymes inhibitors Monika ChauhanRaj Kumar Review Article 16 November 2014 Pages: 2259 - 2282
Medicinal plants of Ecuador: a review of plants with anticancer potential and their chemical composition Natalia Bailon-MoscosoJuan Carlos Romero-BenavidesPatricia Ostrosky-Wegman Review Article 06 February 2015 Pages: 2283 - 2296
Quaternary ammonium and amido derivatives of pyranochromenones and chromenones: synthesis and antimicrobial activity evaluation Suchita PrasadShiv KumarSunil K. Sharma Original Research 12 November 2014 Pages: 2297 - 2313
Anticancer activity and DNA binding property of the dimers of triphenylethylene–coumarin hybrid with two amino side chains Mo ZhuLikai ZhouHua Chen Original Research 12 November 2014 Pages: 2314 - 2324
Potential utility of adenosine 5′-ester prodrugs to enhance its plasma half-life: synthesis and molecular docking studies Eduardo Hernández-VázquezVictoria Chagoya Original Research 16 November 2014 Pages: 2325 - 2335
Co(II), Ni(II), Cu(II) and Zn(II) Complexes of 4-(4-cyanobenzylideneamino)-3-mercapto-5-oxo-1,2,4-triazine: synthesis, characterization and biological studies Kiran SinghSunita RapariaParveen Surain Original Research 20 November 2014 Pages: 2336 - 2346
3D QSAR modeling study on 7-aminofuro [2,3-c] pyridine derivatives as TAK1 inhibitors using CoMFA and COMSIA Pavithra K. BalasubramanianAnand BalupuriSeung Joo Cho Original Research 25 November 2014 Pages: 2347 - 2365
Synthesis and biological evaluation of piperazine derivatives as novel isoform selective voltage-gated sodium (Nav) 1.3 channel modulators Marko JukičRok FrlanDanijel Kikelj Original Research 25 November 2014 Pages: 2366 - 2380
POM analyses of antimicrobial activity of 4H-pyrimido[2,1-b]benzothiazole, pyrazole, and benzylidene derivatives of curcumin Moulay H. YoussoufiPramod K. SahuTaibi Ben Hadda Original Research 27 November 2014 Pages: 2381 - 2392
MIF-1 and Tyr-MIF-1 analogues containing unnatural amino acids: synthesis, biological activity and docking studies Rositsa KalauzkaTatyana DzimbovaTamara Pajpanova Original Research 28 November 2014 Pages: 2393 - 2405
Synthesis and anti-nociceptive, anti-inflammatory activities of new aroyl propionic acid derivatives including N-acylhydrazone motif Gülhan Turan-ZitouniLeyla YurttaşÜmide Demir Özkay Original Research 07 December 2014 Pages: 2406 - 2416
Synthesis and vasorelaxation evaluation of novel biphenyl–furocoumarin derivatives Tao WangCheng WangHuaizhen He Original Research 09 December 2014 Pages: 2417 - 2431
QSAR and pharmacophore modeling of indole-based C-3 pyridone compounds as HCV NS5B polymerase inhibitors utilizing computed molecular descriptors Ankita BatraSisir NandiManish C. Bagchi Original Research 09 December 2014 Pages: 2432 - 2440
Phosphate-hydrolysis, antioxidant, DNA binding, and nuclease activities promoted by heteroleptic nickel(II) phenolate complexes Perumal GurumoorthyAziz Kalilur Rahiman Original Research 12 December 2014 Pages: 2441 - 2453
Benzothiazole derivatives upregulate SIRT1 and relevant genes in high-fat fed C57BL/6J mice Qing GuPenghui ZhouErbing Hua Original Research 12 December 2014 Pages: 2454 - 2460
Synthesis, structure–activity relationships, and bioactivity evaluation of 6-bromo-quinazolinone derivatives Mariarita BaroneVenerando PistaràAndrea Santagati Original Research 13 December 2014 Pages: 2461 - 2475
Synthesis and evaluation of linear furanocoumarins as potential anti-breast and anti-prostate cancer agents Siddheshwar K. ChautheShivani MahajanInder P. Singh Original Research 16 December 2014 Pages: 2476 - 2484
Developing 2D-QSAR models for naphthyridine derivatives against HIV-1 integrase activity Mostafa ZakariazadehAbolfazl BarzegarHassan Aryapour Original Research 17 December 2014 Pages: 2485 - 2504
Anticonvulsant activity of 1,2,4-triazine derivatives with pyridyl side chain: synthesis, biological, and computational study Hamid IrannejadHamid NadriMehdi Khoobi Original Research 18 December 2014 Pages: 2505 - 2513
Synthesis, antibacterial and anticancer evaluation of 5-substituted (1,3,4-oxadiazol-2-yl)quinoline SalahuddinAvijit MazumderMohammad Shaharyar Original Research 18 December 2014 Pages: 2514 - 2528
Tryptophan and thiosemicarbazide derivatives: design, synthesis, and biological evaluation as potential β-d-galactosidase and β-d-glucosidase inhibitors Reema Abu KhalafAhmed Mutanabbi AbdulaMutasem O. Taha Original Research 21 December 2014 Pages: 2529 - 2550
Synthesis, characterization and in vitro antimicrobial evaluation of some novel hydrazone derivatives bearing pyrimidinyl and pyrazolyl moieties as a promising heterocycles Raj KamalVipan KumarKamal Rai Aneja Original Research 06 January 2015 Pages: 2551 - 2560
Identification of new non-steroidal TGR5 agonists using virtual screening with combined pharmacophore models Chen ZhouFangxia ZouXiaoming Zha Original Research 06 January 2015 Pages: 2561 - 2572
Potent CDC25B and PTP1B phosphatase inhibitors: 2′,4′,6′-trihydroxylchalcone derivatives Shui-Lian ZhaoZhou PengLi-Ping Guan Original Research 12 December 2014 Pages: 2573 - 2579
Synthesis, analgesic and anti-inflammatory activities of chalconyl-incorporated hydrazone derivatives of mefenamic acid Neeraj KumarLalit Singh ChauhanRajendra Bera Original Research 22 January 2015 Pages: 2580 - 2590
Synthesis and evaluation of the anti-inflammatory activity of quinoline derivatives Xiang WenShi-Ben WangZhe-Shan Quan Original Research 24 January 2015 Pages: 2591 - 2603
The antimitotic pyrimido[4,5-c]quinolin-1(2H)-one scaffold: probing substituents at position 3 Kamel MetwallyHarris PratsinisDimitris Kletsas Original Research 25 January 2015 Pages: 2604 - 2611
GRID/BIOCUBE4mf to rank the influence of mutations on biological processes to design ad hoc mutants Cecilia RossoGiuseppe ErmondiGiulia Caron Original Research 25 January 2015 Pages: 2612 - 2620
In silico docking studies of non-azadirachtin limonoids against ecdysone receptor of Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae) Ravi Prakash YadavKalibulla Syed IbrahimNachimuthu Senthil Kumar Original Research 28 January 2015 Pages: 2621 - 2631
Synthesis, cyclooxygenase inhibition, and anti-inflammatory evaluation of novel diarylheterocycles with a central pyrazole, pyrazoline, or pyridine ring Khaled R. A. AbdellatifEman K. A. AbdelallGehan M. Kamel Original Research 28 January 2015 Pages: 2632 - 2644
Design, synthesis and in vitro testing of 7-methoxytacrine-amantadine analogues: a novel cholinesterase inhibitors for the treatment of Alzheimer’s disease Katarina SpilovskaJan KorabecnyKamil Kuca Original Research 29 January 2015 Pages: 2645 - 2655
Synthesis and anti-inflammatory in vitro, in silico, and in vivo studies of flavone analogues Manjulatha KhanapurNishal K. PinnaJaishree Badiger Original Research 30 January 2015 Pages: 2656 - 2669
Synthesis and in vitro evaluation of ferutinol aryl esters for estrogenic activity and affinity toward cannabinoid receptors Ahmed M. Galal OsmanEhab A. AbourashedMahmoud A. ElSohly Original Research 31 January 2015 Pages: 2670 - 2678
Antimicrobial/antioxidant activity and POM analyses of novel 7-o-β-d-glucopyranosyloxy-3-(4,5-disubstituted imidazol-2-yl)-4H-chromen-4-ones Kishor HatzadeJaved SheikhTaibi Ben Hadda Original Research 31 January 2015 Pages: 2679 - 2693
High-throughput virtual screening, identification and in vitro biological evaluation of novel inhibitors of signal transducer and activator of transcription 3 Pushpendra SinghFelix Bast Original Research 31 January 2015 Pages: 2694 - 2708
Simple and convenient preparation of some bicyclic alcohols and epoxide derivatives: promising antibiotic activities of (rac)-dimethyl 3,8-dioxatricyclo[3.2.1.02,4]oct-6-ene-6,7-dicarboxylate Özgür YilmazNermin Şimşek KuşMehmet Serdar Gültekin Original Research 03 February 2015 Pages: 2709 - 2716
A click chemistry strategy to synthesize geraniol-coupled 1,4-disubstituted 1,2,3-triazoles and exploration of their microbicidal and antioxidant potential with molecular docking profile Nitin DubeyMukesh C. SharmaPratibha Sharma Original Research 04 February 2015 Pages: 2717 - 2731
Synthesis, antimicrobial and antioxidant activities of imidazotriazoles and new multicomponent reaction toward 5-amino-1-phenyl[1,2,4]triazole derivatives Monia AoualiDhekra MhallaFakher Chabchoub Original Research 05 February 2015 Pages: 2732 - 2741
Novel tetrahydropyrimidine–adamantane hybrids as anti-inflammatory agents: synthesis, structure and biological evaluation Utpalparna KalitaShunan KapingJai Narain Vishwakarma Original Research 08 February 2015 Pages: 2742 - 2755
Synthesis, antibacterial, and DNA-PK evaluation of some novel 6-fluoro-7-(cyclic amino)-2-(thioxo or oxo)-3-substituted quinazolin-4-ones as structural analogues of quinolone and quinazolin-2,4-dione antibiotics Jacob T. HeppellJasim M. A. Al-Rawi Original Research 08 February 2015 Pages: 2756 - 2769
