The State of Alzheimer’s Research and the Path Forward Howard M. FillitB. VellasY. Hara Editorial 24 October 2023 Pages: 617 - 619
Geroscience and Alzheimer’s Disease Drug Development Jeffrey CummingsA. M. Leisgang OsseJ. Kinney Review Open access 24 October 2023 Pages: 620 - 632
Translating the Biology of Aging into New Therapeutics for Alzheimer’s Disease: Senolytics M. RiesslandMiranda E. Orr Review Open access 24 October 2023 Pages: 633 - 646
Fibrin-Targeting Immunotherapy for Dementia A. B. KantorK. AkassoglouJeffrey B. Stavenhagen Review Open access 24 October 2023 Pages: 647 - 660
Opportunities for Cellular Rejuvenation in Alzheimer’s Disease: How Epigenetic Reprogramming and Chaperone-Mediated Autophagy Are Enabling Next Generation Therapeutic Approaches Sharon Rosenzweig-Lipson Review Open access 24 October 2023 Pages: 661 - 668
ASURE Clinical Trial Protocol: A Randomized, Placebo-Controlled, Proof-of-Concept Study Aiming to Evaluate Safety and Target Engagement following Administration of TW001 in Early Alzheimer’s Disease Patients Marlies OosthoekA. LiliE. G. B. Vijverberg Original Research Open access 24 October 2023 Pages: 669 - 674
Modulation of Mitochondrial Function as a Therapeutic Strategy for Neurodegenerative Diseases Eugenia TrushinaT. K. O. NguyenS. Trushin Review Open access 24 October 2023 Pages: 675 - 685
Neuroinflammation, Its Role in Alzheimer’s Disease and Therapeutic Strategies M. KiralyJ. F. FossTony Giordano Review Open access 24 October 2023 Pages: 686 - 698
Targeting Endogenous Mechanisms of Brain Resilience for the Treatment and Prevention of Alzheimer’s Disease H. R. C. ShanksK. M. OnuskaFrank M. Longo Review Open access 24 October 2023 Pages: 699 - 705
Metformin in the Prevention of Alzheimer’s Disease and Alzheimer’s Disease Related Dementias M. TahmiJosé A. Luchsinger Review 24 October 2023 Pages: 706 - 717
Multimodal Precision Prevention - A New Direction in Alzheimer’s Disease M. BarberaD. PereraMiia Kivipelto Review Open access 24 October 2023 Pages: 718 - 728
The Critical Role of Biomarkers for Drug Development Targeting the Biology of Aging M. OwenN. BoseHoward M. Fillit Review Open access 24 October 2023 Pages: 729 - 742
Future of Alzheimer’s Disease Treatment: Combination Therapy and Precision Medicine Howard M. FillitL. K. NisenbaumA. H. Burstein Commentary 24 October 2023 Pages: 743 - 745
Dietary Cholesterol and Dementia Risk Lefkos T. MiddletonE. Riboli Editorial 06 June 2023 Pages: 746 - 747
High Intake of Dietary Cholesterol Decreases the Risk of All-Cause Dementia and AD Dementia: A Results from Framingham Offspring Cohort Mingmin WangYanqiu WangYi Wen Original Research 06 June 2023 Pages: 748 - 755
Preferences about Future Alzheimer’s Disease Treatments Elicited through an Online Survey Using the Threshold Technique Sonia Roldan MunozS. T. de VriesD. Postmus Original Research Open access 30 June 2023 Pages: 756 - 764
Initial Experiences with Amyloid-Related Imaging Abnormalities in Patients Receiving Aducanumab Following Accelerated Approval Matthew D. HoweK. J. BrittonS. P. Salloway Brief Communication 07 August 2023 Pages: 765 - 770
Lecanemab Clarity AD: Quality-of-Life Results from a Randomized, Double-Blind Phase 3 Trial in Early Alzheimer’s Disease Sharon CohenC. H. van DyckL. D. Kramer Original Research Open access 29 September 2023 Pages: 771 - 777
Safety, Tolerability, Pharmacokinetics and Quantitative Electroencephalography Assessment of ACD856, a Novel Positive Allosteric Modulator of Trk-Receptors Following Multiple Doses in Healthy Subjects K. ÖnnestamB. NilssonMärta Segerdahl Original Research Open access 12 July 2023 Pages: 778 - 789
A Randomized Prospective Survey Targeting Knowledge, Barriers, Facilitators and Readiness to Participation in Dementia Research Martha SajatovicL. K. HerrmannC. J. Burant Original Research 03 October 2023 Pages: 790 - 799
Protocol of a Phase II Randomized, Multi-Center, Double-Blind, Placebo-Controlled Trial of S-Adenosyl Methionine in Participants with Mild Cognitive Impairment or Dementia Due to Alzheimer’s Disease Sarah HolperR. WatsonN. Yassi Original Research Open access 15 May 2023 Pages: 800 - 809
Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia Hussein YassineI. C. ArellanesL. S. Schneider Original Research Open access 19 June 2023 Pages: 810 - 820
Reducing the Effects of Ageing on Cognition with Therapeutic Intervention of an Oral Multi-Nutrient: The REACTION Pilot Trial Study Design Christian J. CamargoS. MerrittK. Fernández McInerney Original Research Open access 19 June 2023 Pages: 821 - 827
Two-Year Prognostic Utility of Plasma p217+tau across the Alzheimer’s Continuum A. FeizpourV. DoréChristopher C. Rowe Original Research Open access 05 July 2023 Pages: 828 - 836
Plasma Oligomer β-Amyloid and White Matter Microstructural Integrity in Cognitively Normal Older Adults According to Cerebral Amyloid Deposition S.-M. WangD. W. KangHyun Kook Lim Original Research 10 July 2023 Pages: 837 - 846
The Community Engaged Digital Alzheimer’s Research (CEDAR) Study: A Digital Intervention to Increase Research Participation of Black American Participants in the Brain Health Registry M. R. MindtM. T. AshfordRachel L. Nosheny Original Research Open access 28 March 2023 Pages: 847 - 856
Development of a Mobile-First Registry to Recruit Healthy Volunteers and Members of Underrepresented Communities for Alzheimer’s Disease Prevention Studies R. AggarwalE. Sidnam-MauchJessica Langbaum Original Research Open access 28 June 2023 Pages: 857 - 864
Understanding Barriers and Facilitators to Signing Up for a Mobile-Responsive Registry to Recruit Healthy Volunteers and Members of Underrepresented Communities for Alzheimer’s Disease Prevention Studies D. Neffa-CreechR. AggarwalJessica Langbaum Original Research Open access 06 June 2023 Pages: 865 - 874
Protocol for the Brain Health Support Program Study of the Canadian Therapeutic Platform Trial for Multidomain Interventions to Prevent Dementia (CAN-THUMBS UP): A Prospective 12-Month Intervention Study Howard H. FeldmanS. BellevilleCanadian Consortium on Neurodegeneration in Aging (CCNA), CAN-THUMBS UP Study Group Original Research Open access 15 June 2023 Pages: 875 - 885
Genotypic Effects of the TOMM40’523 Variant and APOE on Longitudinal Cognitive Change over 4 Years: The TOMMORROW Study H. ZouSheng LuoK. A. Welsh-Bohmer Original Research 11 September 2023 Pages: 886 - 894
Social Determinants of Health among Older Adults with Dementia in Urban and Rural Areas Mairead M. BartleyH. Baer-BensonJ. M. Griffin Original Research 07 August 2023 Pages: 895 - 902
Association of Loneliness with Cognitive Functions Kay Thwe KyawA. Levine Original Research 16 May 2023 Pages: 903 - 908
