ExoHCR: a sensitive assay to profile PD-L1 level on tumor exosomes for immunotherapeutic prognosis Lujun HuWenjie ChenGuizhi Zhu Research article Open access 23 November 2020 Pages: 290 - 298
The microgravity enhanced polymer-mediated siRNA gene silence by improving cellular uptake Tongren YangChanchan YuYuanyu Huang Research article Open access 23 November 2020 Pages: 266 - 277
Amphiphilic peptide dendrimer-based nanovehicles for safe and effective siRNA delivery Chi MaDandan ZhuXiaoxuan Liu Research article Open access 21 November 2020 Pages: 278 - 289
Recent advances in the construction of nanozyme-based logic gates Fang PuJinsong RenXiaogang Qu Review Open access 21 November 2020 Pages: 245 - 255
Recent advances of DNAzyme-based nanotherapeutic platform in cancer gene therapy Wendi HuoXiaona LiYi Jin Review Open access 20 November 2020 Pages: 256 - 265
The prototypes of nanozyme-based nanorobots Jiaying XieYiliang JinXiyun Yan Review Open access 20 November 2020 Pages: 223 - 244
Stimuli-responsive polymeric nanomaterials for rheumatoid arthritis therapy Yingsi XieRuslan G. TuguntaevWeisheng Guo Review Open access 06 October 2020 Pages: 193 - 210
Biofriendly micro/nanomotors operating on biocatalysis: from natural to biological environments Ziyi GuoJian LiuKang Liang Review Open access 04 October 2020 Pages: 179 - 192
Recent Endeavors on Molecular Imaging for Mapping Metals in Biology Jing GaoYuncong ChenWeijiang He Review Open access 04 October 2020 Pages: 159 - 178
An efficient autometallography approach to localize lead at ultra-structural levels of cultured cells Han SongGang ZhengWen-Jing Luo Method Open access 28 September 2020 Pages: 211 - 221
The emerging role of tubulin posttranslational modifications in cilia and ciliopathies Kai HeKun LingJinghua Hu Review Open access 24 August 2020 Pages: 89 - 104
Prediction of RNA secondary structure with pseudoknots using coupled deep neural networks Kangkun MaoJun WangYi Xiao Method Open access 04 August 2020 Pages: 146 - 154
“At last in” the physiological roles of the tubular ER network Li LüLiling NiuJunjie Hu Review Open access 04 August 2020 Pages: 105 - 114
Direct structural evidence supporting a revolving mechanism in DNA packaging motors Yao-Gen ShuXiaolin Cheng Commentary Open access 04 August 2020 Pages: 155 - 158
Measurement of viscoelastic properties of injured mouse brain after controlled cortical impact Yu ChenSuhao QiuYuan Feng Method Open access 01 August 2020 Pages: 137 - 145
Epigenetic regulation of covalently closed circular DNA minichromosome in hepatitis B virus infection Zhaoning WangWeiwei WangLanfeng Wang Review Open access 25 July 2020 Pages: 115 - 126
Long-term high-resolution in vivo imaging of cerebral cortical structures following ischemic stroke Lei WangLirui ZhuShengxiang Zhang Protocol Open access 24 June 2020 Pages: 127 - 136
Performance of CHARMM36m with modified water model in simulating intrinsically disordered proteins: a case study Laura I. Gil PinedaLaurie N. MilkoYi He Research article Open access 20 June 2020 Pages: 80 - 87
C-reactive protein in gallbladder diseases: diagnostic and therapeutic insights Ibraheem M. RajabDaniel MajerczykLawrence A. Potempa Review Open access 17 June 2020 Pages: 49 - 67
Epigenetic regulation and mechanobiology Shitian LiDingyi YangQin Peng Invited review Open access 12 June 2020 Pages: 33 - 48
Type II toxin–antitoxin system in bacteria: activation, function, and mode of action Si-Ping ZhangQian WangYong-Xing He Review Open access 11 June 2020 Pages: 68 - 79
Photoacoustic viscoelasticity imaging for the detection of acute hepatitis: a feasibility study Qian WangYujiao Shi Method Open access 13 March 2020 Pages: 1 - 8
Global mapping of live cell mechanical features using PeakForce QNM AFM Jinrong HuShenbao ChenMian Long Protocol Open access 22 January 2020 Pages: 9 - 18
Comparison of immune profiles between hepatocellular carcinoma subtypes Xuemin PanPing LinYixue Li Research article Open access 09 January 2020 Pages: 19 - 32
Regulation of intracellular Ca2+/CaMKII signaling by TRPV4 membrane translocation during osteoblastic differentiation Fen HuYali ZhaoJingjun Xu Research article Open access 22 November 2019 Pages: 254 - 263
Super-resolution microscopy: successful applications in centrosome study and beyond Jingyan FuChuanmao Zhang Invited Review Open access 21 November 2019 Pages: 235 - 243
Refining RNA solution structures with the integrative use of label-free paramagnetic relaxation enhancement NMR Zhou GongShuai YangChun Tang Research article Open access 15 November 2019 Pages: 244 - 253
Natural and engineered bacterial outer membrane vesicles Guangchao QingNingqiang GongXing-Jie Liang Review Open access 01 October 2019 Pages: 184 - 198
Sample preparation method to improve the efficiency of high-throughput single-molecule force spectroscopy Lei JinLi KouXiaodong Hu Method Open access 01 October 2019 Pages: 176 - 183
Towards understanding the mechanisms of proton pumps in Complex-I of the respiratory chain Xuejun C. ZhangBin Li Opinion Open access 01 October 2019 Pages: 219 - 234
Characterization of dendritic cell subtypes in human cord blood by single-cell sequencing Xiaoyang JinLingyuan MengLiguo Zhang Research article Open access 30 September 2019 Pages: 199 - 208
Zinc causes the death of hypoxic astrocytes by inducing ROS production through mitochondria dysfunction Rong PanKe Jian LiuZhifeng Qi Research article Open access 25 September 2019 Pages: 209 - 217
Perilipin 2 and lipid droplets provide reciprocal stabilization Shimeng XuFei ZouPingsheng Liu Research article Open access 12 July 2019 Pages: 145 - 160
An efficient protocol of cryo-correlative light and electron microscopy for the study of neuronal synapses Rong SunYun-Tao LiuGuo-Qiang Bi Protocol Open access 12 July 2019 Pages: 111 - 122
Impact of bacterial chaperonin GroEL–GroES on bacteriorhodopsin folding and membrane integration Xinwei LuBaomei XuFang Huang Research Article Open access 11 July 2019 Pages: 133 - 144
Two chemical-controlled switchable Cas9s for tunable gene editing Meng LiangYang CuiJizhong Lou Communication Open access 04 July 2019 Pages: 161 - 165
Modeling the relationship of diverse genomic signatures to gene expression levels with the regulation of long-range enhancer-promoter interactions Zhen-Xing FengQian-Zhong LiJian-Jun Meng Research Article Open access 24 June 2019 Pages: 123 - 132
CHDOCK: a hierarchical docking approach for modeling Cn symmetric homo-oligomeric complexes Yumeng YanSheng-You Huang Method Open access 29 April 2019 Pages: 65 - 72
P-type ATPases use a domain-association mechanism to couple ATP hydrolysis to conformational change Xuejun C. ZhangHongwei Zhang Opinion Open access 29 April 2019 Pages: 167 - 175
Identification of key genes and pathways for Alzheimer’s disease via combined analysis of genome-wide expression profiling in the hippocampus Mengsi WuKechi FangJing Wang Research Article Open access 20 April 2019 Pages: 98 - 109
A light-addressable microfluidic device for label-free functional assays of bioengineered taste receptor cells via extracellular recording Liping DuWei ChenChunsheng Wu Method Open access 20 April 2019 Pages: 73 - 79
A protocol for structured illumination microscopy with minimal reconstruction artifacts Junchao FanXiaoshuai HuangLiangyi Chen Protocol Open access 19 April 2019 Pages: 80 - 90
A new co-culture method for identifying synaptic adhesion molecules involved in synapse formation Wei JiangJihong GongXiaofei Yang Protocol Open access 12 March 2019 Pages: 91 - 97
Towards a multiphysics modelling framework for thermosensitive liposomal drug delivery to solid tumour combined with focused ultrasound hyperthermia Wenbo ZhanWladyslaw GedroycXiao Yun Xu Research Article Open access 05 March 2019 Pages: 43 - 59
Detection of cancer cells based on glycolytic-regulated surface electrical charges Wenjun LeBingdi ChenDonglu Shi Review Open access 01 March 2019 Pages: 10 - 18
A genetically encoded ratiometric calcium sensor enables quantitative measurement of the local calcium microdomain in the endoplasmic reticulum Chen LuoHuiyu WangPingyong Xu Research article Open access 27 February 2019 Pages: 31 - 42
Co-encapsulation of curcumin and doxorubicin in albumin nanoparticles blocks the adaptive treatment tolerance of cancer cells Seyed Mohammad MotevalliAhmed Shaker EltahanXing-Jie Liang Research article Open access 11 January 2019 Pages: 19 - 30
Protocol for analyzing protein liquid–liquid phase separation Zheng WangGangming ZhangHong Zhang Protocol Open access 05 December 2018 Pages: 1 - 9
Energy coupling mechanism of FO in a rotary ATP synthase: a model update Xuejun C. ZhangMin Liu Opinion Open access 03 December 2018 Pages: 61 - 64
Thermodynamics of voltage-gated ion channels Xuejun C. ZhangHanting YangFei Sun Review Open access 16 November 2018 Pages: 300 - 319