1. ADR update from Health Canada

   News item 01 February 2013 Pages: 2 - 2

2. Dietary supplement `Vinarol' withdrawn

   News item 01 February 2013 Pages: 2 - 2

3. Elevated risk of VTE with `Diane-35'

   News item 01 February 2013 Pages: 2 - 2

4. Greater transparency needed in safety regulation

   Comment 01 February 2013 Pages: 3 - 3

5. Intolerance to antihypertensives linked to psychiatric morbidity

   Clinical study 01 February 2013 Pages: 3 - 3

6. Smallpox vaccine: cardiac events prompt recommendation update

   News item 01 February 2013 Pages: 3 - 3

7. Magnesium prevents ibutilide-associated torsade de pointes?

   Clinical study 01 February 2013 Pages: 4 - 4

8. Thalidomide increases risk of VTE in patients receiving docetaxel

   Clinical study 01 February 2013 Pages: 4 - 4

9. Antineoplastics: no affect on intellectual outcome in ALL

   Non-clinical study 01 February 2013 Pages: 5 - 5

10. HRT: increased risk of irritable bowel syndrome

    Incidence study 01 February 2013 Pages: 5 - 5

11. No increase in acute MI with selective COX-2 inhibitors

    Incidence study 01 February 2013 Pages: 5 - 5

12. Sevoflurane prolongs QT interval in infants

    Clinical study 01 February 2013 Pages: 5 - 5

13. SSRIs increase risk of GI bleeding

    Incidence study 01 February 2013 Pages: 5 - 5

14. Antibacterials

    Case report 01 February 2013 Pages: 6 - 6

15. Botulinum toxin A

    Case reports 01 February 2013 Pages: 6 - 6

16. Bupropion

    Case report 01 February 2013 Pages: 6 - 6

17. Chlorambucil/melphalan

    Case report 01 February 2013 Pages: 6 - 6

18. Clopidogrel interaction

    Case reports 01 February 2013 Pages: 6 - 7

19. Dalteparin/enoxaparin

    Case report 01 February 2013 Pages: 7 - 7

20. Desipramine interaction

    Case report 01 February 2013 Pages: 7 - 7

21. Dextran

    Case report 01 February 2013 Pages: 7 - 7

22. Docetaxel

    Case report 01 February 2013 Pages: 7 - 7

23. Docetaxel

    Case reports 01 February 2013 Pages: 8 - 8

24. Glucagon

    Case reports 01 February 2013 Pages: 8 - 8

25. Irinotecan

    Case report 01 February 2013 Pages: 8 - 8

26. Iron overdose

    Case report 01 February 2013 Pages: 8 - 8

27. Isotretinoin/psoralens

    Case report 01 February 2013 Pages: 9 - 9

28. Methotrexate

    Case report 01 February 2013 Pages: 9 - 9

29. Minoxidil/Serenoa repens

    Case report 01 February 2013 Pages: 9 - 9

30. Naproxen

    Case report 01 February 2013 Pages: 9 - 10

31. Olanzapine

    Case report 01 February 2013 Pages: 10 - 10

32. Pamidronic acid

    Case report 01 February 2013 Pages: 10 - 10

33. Prednisone withdrawal/zafirlukast

    Case reports 01 February 2013 Pages: 10 - 10

34. Propofol

    Case report 01 February 2013 Pages: 10 - 10

35. Somatropin

    Case report 01 February 2013 Pages: 11 - 11

36. Trastuzumab

    Case report 01 February 2013 Pages: 11 - 11

37. Tretinoin

    Case report 01 February 2013 Pages: 11 - 11

38. Venlafaxine/zolpidem overdose

    Case report 01 February 2013 Pages: 11 - 12