1. Health Canada shifts focus on drug regulation

   News item 18 January 2013 Pages: 1 - 1

2. Permax withdrawn from Chinese market

   Media release 18 January 2013 Pages: 2 - 2

3. The US FDA is permitting the restricted use of Zelnorm [tegaserod] under a treatment investigational new drug protocol

   Media release 18 January 2013 Pages: 2 - 2

4. The US FDA has placed a clinical hold on an investigational gene therapy product for the treatment of active inflammatory arthritis

   Media release 18 January 2013 Pages: 2 - 2

5. Thiazolidinediones may increase risk of heart failure

   Clinical study 18 January 2013 Pages: 3 - 3

6. Avandia remains an option in the US

   News item 18 January 2013 Pages: 3 - 3

7. GSK takes issue with Cochrane rosiglitazone review

   News item 18 January 2013 Pages: 3 - 3

8. Minorities at greater risk of warfarin-related ICH

   News item 18 January 2013 Pages: 4 - 4

9. VICTOR analysis shows increased CV events with Vioxx

   Clinical study 18 January 2013 Pages: 4 - 4

10. Cases of active tuberculosis (TB) in tumour necrosis factor (TNF) antagonist recipients continue to occur due to noncompliance with recommendations

    Clinical study 18 January 2013 Pages: 4 - 4

11. Inhospital use of opioids increases the occurrence of postoperative paralytic ileus

    Clinical study 18 January 2013 Pages: 4 - 4

12. Adalimumab

    Case report 18 January 2013 Pages: 5 - 5

13. Amiodarone/quinidine

    Case report 18 January 2013 Pages: 5 - 5

14. Adalimumab/etanercept/infliximab

    Case report 18 January 2013 Pages: 5 - 5

15. Azathioprine/methylprednisolone

    Case reports 18 January 2013 Pages: 6 - 6

16. Amoxicillin

    Case report 18 January 2013 Pages: 6 - 6

17. Antiretrovirals

    Case report 18 January 2013 Pages: 6 - 6

18. Antithymocyte globulin

    Case report 18 January 2013 Pages: 6 - 6

19. Bexarotene

    Case report 18 January 2013 Pages: 7 - 7

20. Botulinum toxin A

    Case report 18 January 2013 Pages: 7 - 7

21. Baclofen

    Case report 18 January 2013 Pages: 7 - 7

22. Bevacizumab

    Case report 18 January 2013 Pages: 7 - 7

23. Bupivacaine/fentanyl

    Case report 18 January 2013 Pages: 8 - 8

24. Ciclosporin/corticosteroids

    Case report 18 January 2013 Pages: 8 - 8

25. Cisplatin/epirubicin/methotrexate

    Case report 18 January 2013 Pages: 8 - 8

26. Capecitabine

    Case report 18 January 2013 Pages: 8 - 8

27. Colchicine overdose

    Case report 18 January 2013 Pages: 9 - 9

28. Clozapine interaction

    Case report 18 January 2013 Pages: 9 - 9

29. Cisplatin/gemcitabine

    Case report 18 January 2013 Pages: 9 - 9

30. Dexamethasone/thalidomide

    Case report 18 January 2013 Pages: 10 - 10

31. Dexamethasone/doxorubicin

    Case report 18 January 2013 Pages: 10 - 10

32. Donepezil/memantine

    Case report 18 January 2013 Pages: 10 - 11

33. Etanercept

    Case report 18 January 2013 Pages: 11 - 11

34. Doxorubicin

    Case report 18 January 2013 Pages: 11 - 11

35. Ethambutol

    Case report 18 January 2013 Pages: 11 - 11

36. Drug-eluting stent

    Case report 18 January 2013 Pages: 11 - 11

37. Fluorouracil

    Case report 18 January 2013 Pages: 12 - 12

38. Gabapentin

    Case report 18 January 2013 Pages: 12 - 12

39. Gadodiamide

    Case report 18 January 2013 Pages: 13 - 13

40. Gemcitabine

    Case report 18 January 2013 Pages: 13 - 13

41. Gabapentin interaction

    Case report 18 January 2013 Pages: 13 - 13

42. Granulocyte colony-stimulating factors

    Case report 18 January 2013 Pages: 14 - 14

43. Hydroxychloroquine

    Case report 18 January 2013 Pages: 14 - 14

44. Green tea

    Case report 18 January 2013 Pages: 14 - 14

45. Immune globulin

    Case report 18 January 2013 Pages: 15 - 15

46. Indinavir

    Case report 18 January 2013 Pages: 15 - 15

47. Indapamide

    Case report 18 January 2013 Pages: 15 - 15

48. Infliximab

    Case report 18 January 2013 Pages: 16 - 16

49. Interferon-β-1a

    Case report 18 January 2013 Pages: 16 - 16

50. Insulin

    Case report 18 January 2013 Pages: 16 - 16