1. Improving detection and reporting of harms in healthcare

   News item 23 January 2013 Pages: 2 - 2

2. Trials supporting selective COX-2 inhibitor safety seriously flawed

   Comment 23 January 2013 Pages: 2 - 2

3. UK MCA criticised by MPs

   News item 23 January 2013 Pages: 2 - 2

4. 'Topamax' label update: risk of oligohidrosis and hyperthermia

   Correspondence 23 January 2013 Pages: 3 - 3

5. Canada warns against 'Paxil' use in children and adolescents

   News item 23 January 2013 Pages: 3 - 3

6. Explicit liver function monitoring directions added to 'Arava' label

   News item 23 January 2013 Pages: 3 - 3

7. Methotrexate errors to be reduced in the UK

   News item 23 January 2013 Pages: 3 - 3

8. Alosetron: no increase in colonic complications

   Incidence study 23 January 2013 Pages: 4 - 4

9. Atypical antipsychotics: adverse effect profile linked to treatment costs

   Clinical study 23 January 2013 Pages: 4 - 4

10. Azathioprine associated with increased risk of pancreatitis

    Incidence study 23 January 2013 Pages: 4 - 4

11. Genetic risk factors for somatropin-transmitted CJD

    Clinical study 23 January 2013 Pages: 4 - 4

12. Fluoroquinolones: higher rate of AEs in paediatric patients

    Clinical study 23 January 2013 Pages: 5 - 5

13. Linezolid: no significant risk of haematological disorders

    Clinical study 23 January 2013 Pages: 5 - 5

14. Liposomal amphotericin B: high rate of infusion-related reactions

    Incidence study 23 January 2013 Pages: 5 - 5

15. Methadone dose predictive of QTc interval prolongation

    Clinical study 23 January 2013 Pages: 5 - 5

16. Raloxifene decreases plasma antithrombin activity

    Clinical study 23 January 2013 Pages: 5 - 5

17. Gene polymorphisms not predictors of levodopa AEs

    Clinical study 23 January 2013 Pages: 6 - 6

18. SSRIs + NSAIDs: increased risk of GI adverse effects

    Clinical study 23 January 2013 Pages: 6 - 6

19. Amoxicillin/clavulanic acid

    Case report 23 January 2013 Pages: 7 - 7

20. Amphotericin B liposomal

    Case report 23 January 2013 Pages: 7 - 7

21. Benfluorex

    Case report 23 January 2013 Pages: 7 - 7

22. Botulinum toxin

    Case report 23 January 2013 Pages: 7 - 8

23. Cefazolin

    Case report 23 January 2013 Pages: 8 - 8

24. Ciprofloxacin

    Case report 23 January 2013 Pages: 8 - 8

25. Cyclosporin

    Case report 23 January 2013 Pages: 8 - 8

26. Didanosine/indinavir/stavudine

    Case report 23 January 2013 Pages: 8 - 9

27. Digoxin interaction

    Case report 23 January 2013 Pages: 9 - 9

28. Docetaxel/fluorouracil

    Case report 23 January 2013 Pages: 9 - 9

29. Donepezil

    Case report 23 January 2013 Pages: 9 - 10

30. Donepezil/maprotiline

    Case report 23 January 2013 Pages: 10 - 10

31. Efavirenz/lamivudine/stavudine

    Case report 23 January 2013 Pages: 10 - 10

32. Enalapril

    Case report 23 January 2013 Pages: 10 - 10

33. Fluoxetine

    Case report 23 January 2013 Pages: 10 - 10

34. Gemfibrozil

    Case report 23 January 2013 Pages: 11 - 11

35. Hydroxycarbamide

    Case report 23 January 2013 Pages: 11 - 11

36. Hydroxycarbamide

    Case report 23 January 2013 Pages: 11 - 11

37. Immunosuppressants

    Case report 23 January 2013 Pages: 11 - 12

38. Infliximab

    Case report 23 January 2013 Pages: 12 - 12

39. Infliximab

    Case report 23 January 2013 Pages: 12 - 12

40. Levobupivacaine

    Case report 23 January 2013 Pages: 12 - 12

41. Levofloxacin

    Case report 23 January 2013 Pages: 12 - 12

42. Linezolid

    Case report 23 January 2013 Pages: 13 - 13

43. Lithium

    Case reports 23 January 2013 Pages: 13 - 13

44. Methylprednisolone

    Case report 23 January 2013 Pages: 13 - 13

45. Metoclopramide

    Case report 23 January 2013 Pages: 13 - 13

46. Mitoxantrone

    Case report 23 January 2013 Pages: 13 - 14

47. Olanzapine

    Case report 23 January 2013 Pages: 14 - 14

48. Paclitaxel

    Case report 23 January 2013 Pages: 14 - 14

49. Promazine overdose

    Case report 23 January 2013 Pages: 14 - 14

50. Quinupristin/dalfopristin

    Case report 23 January 2013 Pages: 14 - 15