1. Labelling changes in the US

   News item 09 February 2013 Pages: 2 - 2

2. ADR update from Canada

   News item 09 February 2013 Pages: 3 - 3

3. Interferon-α-2b impairs platelet aggregation

   Clinical study 09 February 2013 Pages: 3 - 3

4. Oxaliplatin: hypersensitivity

   Clinical study 09 February 2013 Pages: 4 - 4

5. Trastuzumab: increased risk of cardiac dysfunction

   Incidence study 09 February 2013 Pages: 4 - 4

6. Warfarin: CYP2C9 polymorphisms increase risk of bleeding events

   Incidence study 09 February 2013 Pages: 4 - 4

7. Amlodipine

   Case report 09 February 2013 Pages: 5 - 5

8. Ciprofloxacin increases risk of achilles tendonitis in lung transplant recipients

   Incidence study 09 February 2013 Pages: 5 - 5

9. Interferon-α-2a: increases severity of depressive symptoms

   Incidence study 09 February 2013 Pages: 5 - 5

10. Cerivastatin interaction

    Case report 09 February 2013 Pages: 5 - 6

11. Cerivastatin interaction

    Case report 09 February 2013 Pages: 6 - 6

12. Danazol interaction

    Case report 09 February 2013 Pages: 6 - 6

13. Diphenhydramine interaction

    Case report 09 February 2013 Pages: 6 - 6

14. Disopyramide

    Case report 09 February 2013 Pages: 7 - 7

15. Etanercept

    Case reports 09 February 2013 Pages: 7 - 7

16. Etanercept/infliximab

    Case report 09 February 2013 Pages: 7 - 7

17. Flupenthixol

    Case report 09 February 2013 Pages: 7 - 7

18. Imatinib mesylate

    Case report 09 February 2013 Pages: 7 - 8

19. Infliximab

    Case report 09 February 2013 Pages: 8 - 8

20. Infliximab

    Case report 09 February 2013 Pages: 8 - 8

21. Insulins

    Case report 09 February 2013 Pages: 8 - 9

22. Interferon-α-2b

    Case report 09 February 2013 Pages: 9 - 9

23. Leflunomide

    Case report 09 February 2013 Pages: 9 - 9

24. Levodopa

    Case report 09 February 2013 Pages: 9 - 9

25. Levodopa

    Case report 09 February 2013 Pages: 9 - 9

26. Lisinopril

    Case reports 09 February 2013 Pages: 9 - 10

27. Methotrexate

    Case reports 09 February 2013 Pages: 10 - 10

28. Methotrexate

    Case report 09 February 2013 Pages: 10 - 10

29. Nilvadipine interaction

    Case report 09 February 2013 Pages: 10 - 10

30. Remifentanil

    Case report 09 February 2013 Pages: 10 - 11

31. Sertraline/tramadol

    Case report 09 February 2013 Pages: 11 - 11

32. Tacrolimus

    Case report 09 February 2013 Pages: 11 - 11

33. Tacrolimus

    Case report 09 February 2013 Pages: 11 - 11

34. Tacrolimus interaction

    Case report 09 February 2013 Pages: 11 - 11

35. Topotecan

    Case report 09 February 2013 Pages: 12 - 12