1. Updates from the UK CSM and MCA

   News item 18 January 2013 Pages: 2 - 2

2. Warning added to `Coumadin' labelling

   Media release 18 January 2013 Pages: 2 - 2

3. No currently available NSAIDs spare gastric COX activity

   Volunteers 18 January 2013 Pages: 3 - 3

4. No obvious abuse potential with sibutramine

   Volunteers 18 January 2013 Pages: 3 - 3

5. Pyridoxine is `safe' at daily doses ≤ 200mg

   News item 18 January 2013 Pages: 3 - 3

6. Increased serum triglyceride levels occurred in 4/9 renal transplant recipients receiving sirolimus

   Clinical study 18 January 2013 Pages: 4 - 4

7. Neurovisual impairment with interferon-α-2b

   Incidence study 18 January 2013 Pages: 4 - 4

8. OCs and VTE: German findings

   Incidence study 18 January 2013 Pages: 4 - 4

9. Perioperative bupivacaine was not associated with cholestasis

   Clinical study 18 January 2013 Pages: 4 - 4

10. Venlafaxine had no significant effect on driving performance, but was associated with decreased vigilance

    Volunteers 18 January 2013 Pages: 4 - 4

11. First trimester in utero corticosteroid exposure

    Incidence study 18 January 2013 Pages: 5 - 5

12. Intermediate-dose methotrexate and neurotoxicity in children

    Incidence study 18 January 2013 Pages: 5 - 5

13. NSAIDs + diuretics increase risk of CHF in elderly patients

    Incidence study 18 January 2013 Pages: 5 - 5

14. Paronychia of the great toes in indinavir recipients

    Incidence study 18 January 2013 Pages: 5 - 5

15. Antineoplastics

    Case report 18 January 2013 Pages: 6 - 6

16. Bleomycin

    Case report 18 January 2013 Pages: 6 - 6

17. Carbimazole/propylthiouracil

    Case report 18 January 2013 Pages: 6 - 6

18. Clarithromycin

    Case report 18 January 2013 Pages: 6 - 7

19. Cloxacillin

    Case report 18 January 2013 Pages: 7 - 7

20. Dapsone

    Case report 18 January 2013 Pages: 7 - 7

21. Digoxin interaction

    Case report 18 January 2013 Pages: 7 - 7

22. Dopamine

    Case reports 18 January 2013 Pages: 7 - 7

23. Flutamide

    Case report 18 January 2013 Pages: 8 - 8

24. Heparin

    Case report 18 January 2013 Pages: 8 - 8

25. Ibuprofen

    Case reports 18 January 2013 Pages: 8 - 8

26. Indinavir

    Case report 18 January 2013 Pages: 9 - 9

27. Interferon-α-2a

    Case report 18 January 2013 Pages: 9 - 9

28. Ivermectin

    Case reports 18 January 2013 Pages: 9 - 10

29. Lamotrigine

    Case report 18 January 2013 Pages: 10 - 10

30. Lanoconazole

    Case report 18 January 2013 Pages: 10 - 10

31. Macrogols

    Case reports 18 January 2013 Pages: 10 - 10

32. Metronidazole

    Case report 18 January 2013 Pages: 10 - 10

33. Morphine overdose

    Case report 18 January 2013 Pages: 11 - 11

34. Phenylephrine

    Case report 18 January 2013 Pages: 12 - 12

35. Roxithromycin

    Case report 18 January 2013 Pages: 12 - 12

36. Sumatriptan

    Case report 18 January 2013 Pages: 12 - 12

37. Tegafur-uracil

    Case report 18 January 2013 Pages: 12 - 12