1. EMEA concludes SSRIs and SNRIs not for use in children, adolescents

   News item 21 January 2013 Pages: 2 - 2

2. Letter reminds of hepatotoxicity with beta interferons

   News item 21 January 2013 Pages: 2 - 2

3. Reminyl: increased mortality in mild cognitive impairment

   News item 21 January 2013 Pages: 2 - 2

4. Xigris only for use in high-risk patients

   News item 21 January 2013 Pages: 2 - 2

5. In utero valproic acid exposure may increase risk of congenital disorders

   News item 21 January 2013 Pages: 3 - 3

6. Confidence in GP management of depression needs to be restored

   Comment 21 January 2013 Pages: 3 - 3

7. Warning letter makes little difference for tramadol recipients

   Clinical study 21 January 2013 Pages: 3 - 3

8. Antiepileptic drugs alter bone mineral density

   News item 21 January 2013 Pages: 4 - 4

9. Aspirin increases intracerebral haemorrhage risk after alteplase treatment

   Clinical study 21 January 2013 Pages: 4 - 4

10. Higher sedation rates with phenobarbital, phenytoin and primidone than with other AEDs

    Clinical study 21 January 2013 Pages: 4 - 4

11. NSAID use may increase risk of acute renal failure

    Clinical study 21 January 2013 Pages: 4 - 4

12. Pooled analysis shows increased mortality with nesiritide

    Clinical study 21 January 2013 Pages: 4 - 4

13. Valproic acid: higher incidence of polycystic ovary syndrome than lamotrigine

    Clinical study 21 January 2013 Pages: 4 - 4

14. Fluoroquinolones: anaphylaxis a class effect?

    Clinical study 21 January 2013 Pages: 5 - 5

15. More serious ADRs with amoxicillin/clavulanic acid than with amoxicillin

    Clinical study 21 January 2013 Pages: 5 - 5

16. Risk of endometrial polyp occurrence differs by HRT protocol

    Clinical study 21 January 2013 Pages: 5 - 5

17. Torsade de pointes risk with psychotropics seen in a heart beat

    Clinical study 21 January 2013 Pages: 5 - 5

18. Anaesthetics

    Case report 21 January 2013 Pages: 6 - 6

19. Benzylthiouracil

    Case report 21 January 2013 Pages: 6 - 6

20. Betamethasone dipropionate/betamethasone valerate/fluocinolone acetonide

    Case report 21 January 2013 Pages: 6 - 6

21. Bortezomib

    Case report 21 January 2013 Pages: 6 - 7

22. Ciclosporin

    Case report 21 January 2013 Pages: 7 - 7

23. Clozapine

    Case report 21 January 2013 Pages: 7 - 7

24. Dexketoprofen

    Case report 21 January 2013 Pages: 7 - 7

25. Dipyridamole

    Case report 21 January 2013 Pages: 7 - 7

26. Eletriptan/naratriptan/sumatriptan

    Case reports 21 January 2013 Pages: 8 - 8

27. Enfuvirtide

    Case report 21 January 2013 Pages: 8 - 8

28. Escitalopram

    Case report 21 January 2013 Pages: 8 - 8

29. General anaesthetics

    Case report 21 January 2013 Pages: 8 - 9

30. Herbal medicines

    Case report 21 January 2013 Pages: 9 - 9

31. Herbal medicines

    Case report 21 January 2013 Pages: 9 - 9

32. Ibuprofen

    Case report 21 January 2013 Pages: 9 - 9

33. Imiquimod

    Case reports 21 January 2013 Pages: 10 - 10

34. Interferon-α

    Case report 21 January 2013 Pages: 10 - 10

35. Interleukin-2

    Case report 21 January 2013 Pages: 10 - 10

36. Isotretinoin

    Case report 21 January 2013 Pages: 11 - 11

37. Lidocaine

    Case report 21 January 2013 Pages: 11 - 11

38. Lopinavir/ritonavir

    Case reports 21 January 2013 Pages: 11 - 11

39. Midazolam

    Case report 21 January 2013 Pages: 12 - 12

40. Nateglinide overdose

    Case report 21 January 2013 Pages: 12 - 12

41. Peginterferon-α

    Case report 21 January 2013 Pages: 12 - 12

42. Peginterferon-α-2a/ribavirin

    Case report 21 January 2013 Pages: 12 - 13

43. Peginterferon-α-2b

    Case report 21 January 2013 Pages: 13 - 13

44. Pegvisomant

    Case report 21 January 2013 Pages: 13 - 13

45. Terbinafine

    Case report 21 January 2013 Pages: 13 - 13

46. Tinzaparin sodium

    Case report 21 January 2013 Pages: 14 - 14

47. Valdecoxib

    Case report 21 January 2013 Pages: 14 - 14

48. Valproic acid overdose

    Case report 21 January 2013 Pages: 14 - 14

49. Ziprasidone

    Case report 21 January 2013 Pages: 14 - 15