1. Foreword

   • Christopher-Paul Milne

   EditorialNotes 07 February 2013 Pages: 1 - 3

2. Health Reform in the US

   • Robert B. Helms

   Review Article 07 February 2013 Pages: 5 - 14

3. What Works and What Doesn’t Work Well in the US Healthcare System

   • Harold S. Luft

   Review Article 07 February 2013 Pages: 15 - 28

4. What an Informed Patient Means for the Future of Healthcare

   • Ruth M. Parker

   Review Article 07 February 2013 Pages: 29 - 33

5. The Impact of Therapeutic Reference Pricing on Innovation in Cardiovascular Medicine

   • Desmond Sheridan
   • Jim Attridge

   Current Opinion 07 February 2013 Pages: 35 - 54

6. Disease Management Programmes in Germany

   • Stefan Felder

   Review Article 07 February 2013 Pages: 55 - 57

7. Do Health-Related Labour Costs Weaken the Competitiveness of the Economy?

   • Bertram Häussler
   • Thomas Ecker
   • Markus Schneider

   Original Research 07 February 2013 Pages: 59 - 68

8. The Impact of Incremental Innovation in Biopharmaceuticals

   • Ernst R. Berndt
   • Iain M. Cockburn
   • Karen A. Grépin

   Original Research 07 February 2013 Pages: 69 - 86

9. Transatlantic Convergence with Respect to the Fourth Hurdle?

   • Joshua Cohen

   Review Article 07 February 2013 Pages: 87 - 94

10. Political Challenges for Healthcare Reform

    • Lawrence D. Brown

    Review Article 07 February 2013 Pages: 95 - 99

11. Lean Systems Approaches to Health Technology Assessment

    • John F. P. Bridges

    Current Opinion 07 February 2013 Pages: 101 - 109

12. Building a Competitive Insurance System

    • Peter Zweifel

    Review Article 07 February 2013 Pages: 111 - 119

13. Concluding Remarks

    • Kenneth I. Kaitin

    Concluding Remarks 07 February 2013 Pages: 121 - 122