Articles

1. Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians

   • Kevin Meesters
   • Violeta Balbas-Martinez
   • Robin Michelet

   Review Article 16 May 2024

   

2. Advances in Immune Tolerance Induction in Enzyme Replacement Therapy

   • Aslı İnci
   • Fatih Süheyl Ezgü
   • Leyla Tümer

   Review Article Open access 25 April 2024 Pages: 287 - 308

3. Perforated Appendicitis in Children: Management, Microbiology, and Antibiotic Stewardship

   • Katherine B. Snyder
   • Catherine J. Hunter
   • Christie L. Buonpane

   Review Article 24 April 2024 Pages: 277 - 286

4. CROCuS, a Phase II Study Evaluating the Antiviral Activity, Clinical Outcomes, and Safety of Rilematovir in Children Aged ≥ 28 Days and ≤ 3 Years with Acute Respiratory Tract Infection Due to Respiratory Syncytial Virus

   • Fernando Ferrero
   • Chien-Yu Lin
   • the CROCuS Investigators

   Original Research Article Open access 22 April 2024

   

5. Dapagliflozin and Empagliflozin in Paediatric Indications: A Systematic Review

   • Sebastiano A. G. Lava
   • Craig Laurence
   • Oscar Della Pasqua

   Systematic Review 18 April 2024 Pages: 229 - 243

   

6. Population Pharmacokinetics of Adalimumab in Juvenile Idiopathic Arthritis Patients: A Retrospective Cohort Study Using Clinical Care Data

   • Amara Nassar-Sheikh Rashid
   • Femke Hooijberg
   • Ron A. A. Mathôt

   Original Research Article Open access 17 April 2024

   

7. Distribution of Bevacizumab into the Cerebrospinal Fluid of Children and Adolescents with Recurrent Brain Tumors

   • Iris K. Minichmayr
   • Ursula Knaack
   • Andreas Peyrl

   Original Research Article Open access 08 April 2024

   

8. Neonatal Necrotizing Enterocolitis: An Update on Pathophysiology, Treatment, and Prevention

   • Annette Gawron Roberts
   • Noelle Younge
   • Rachel Gottron Greenberg

   Review Article 02 April 2024 Pages: 259 - 275

   

9. Comparison of Deep and Moderate Neuromuscular Blockade for Major Laparoscopic Surgery in Children: A Randomized Controlled Trial

   • Guo Wei
   • Yong-Xin Li
   • Shou-Dong Pan

   Original Research Article 21 March 2024 Pages: 347 - 353

   

10. The Effect of Polymorphisms and Other Biomarkers on Infliximab Exposure in Paediatric Inflammatory Bowel Disease: Development of a Population Pharmacokinetic Model

    • Susana Clemente-Bautista
    • Iñaki F. Trocóniz
    • Marta Miarons

    Original Research Article 20 March 2024 Pages: 331 - 346

    

11. Treatment Options for Alopecia Areata in Children and Adolescents

    • Linnea L. Westerkam
    • Diana B. McShane
    • Dean S. Morrell

    Review Article 11 March 2024 Pages: 245 - 257

12. Practical Approach to Diagnosis and Management of IL-1-Mediated Autoinflammatory Diseases (CAPS, TRAPS, MKD, and DIRA)

    • Kader Cetin Gedik
    • Zehra Serap Arici
    • Erkan Demirkaya

    Therapy in Practice 20 February 2024 Pages: 113 - 126

    

13. Correction: Enteral and Parenteral Treatment with Caffeine for Preterm Infants in the Delivery Room: A Randomised Trial

    • Carlo Dani
    • Alessandra Cecchi
    • Luca Boni

    Correction Open access 16 February 2024 Pages: 215 - 215

14. Existing and Emerging Targeted Therapies in Juvenile Psoriatic Arthritis: Challenges and Unmet Needs

    • Sarrah Lokhandwala
    • Jaiden Townsend
    • Coziana Ciurtin

    Leading Article 04 February 2024 Pages: 217 - 228

    

15. Oral Ibuprofen for the Treatment of PDA in Preterm Neonates: Urgent Need for a Safer Alternative to Hyperosmolar Formulations

    • Jaemaela del Rosario
    • Gerhard Fusch
    • Samira Samiee-Zafarghandy

    Research Letter 27 January 2024 Pages: 205 - 207

    

16. Improving Methylphenidate Titration in Children with Attention-Deficit/Hyperactivity Disorder (ADHD): A Randomized Controlled Trial Using Placebo-Controlled Titration Implemented in Clinical Practice

    • Karen Vertessen
    • Marjolein Luman
    • Jaap Oosterlaan

    Original Research Article 27 January 2024 Pages: 319 - 330

    

17. Real-World Data on the Use of Sirolimus in Asian Children with Vascular Malformations

    • Lu Yu
    • Zigang Xu
    • Li Li

    Original Research Article 27 January 2024 Pages: 309 - 317

    

18. Infections in Children Aged 6 Months to 5 Years Treated with Dupilumab in a Placebo-Controlled Clinical Trial of Moderate-to-Severe Atopic Dermatitis

    • Amy S. Paller
    • Elaine C. Siegfried
    • Sonya L. Cyr

    Original Research Article Open access 24 January 2024 Pages: 163 - 173

    

19. Use of Computerized Physician Order Entry with Clinical Decision Support to Prevent Dose Errors in Pediatric Medication Orders: A Systematic Review

    • Henna Ruutiainen
    • Anna-Riia Holmström
    • Sini Kuitunen

    Systematic Review Open access 19 January 2024 Pages: 127 - 143

    

20. Therapeutic Drug Monitoring of Voriconazole in Critically Ill Pediatric Patients: A Single-Center Retrospective Study

    • Khalid W. Taher
    • Razan Almofada
    • Abdullah Alsultan

    Original Research Article 16 January 2024 Pages: 197 - 203

21. Safety and Effectiveness of Prucalopride in Children with Functional Constipation with and without Upper Symptoms

    • Alejandro Velez
    • Ajay Kaul
    • Neha R. Santucci

    Original Research Article 04 January 2024 Pages: 187 - 195

    

22. Toxicity Spectrum of Anti-GD2 Immunotherapy: A Real-World Study Leveraging the US Food and Drug Administration Adverse Event Reporting System

    • Guangfei Wang
    • Jinglin Wang
    • Zhiping Li

    Original Research Article 28 December 2023 Pages: 175 - 185

    

23. Acknowledgement to Referees

    Acknowledgement to Referees 21 December 2023 Pages: 1 - 3

24. Managing Lupus Nephritis in Children and Adolescents

    • Eugene Yu-hin Chan
    • Fiona Fung-yee Lai
    • Tak Mao Chan

    Review Article 20 December 2023 Pages: 145 - 161

    

25. Incidence of Antimicrobial-Associated Acute Kidney Injury in Children: A Structured Review

    • Torsten Joerger
    • Molly Hayes
    • Kevin J. Downes

    Review Article 13 December 2023 Pages: 59 - 70

    

26. Bosutinib: Pediatric First Approval

    • Sheridan M. Hoy

    AdisInsight Report 07 December 2023 Pages: 209 - 214

    

27. Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children: Rationale and Progress to Date

    • Charl Verwey
    • Ziyaad Dangor
    • Shabir A. Madhi

    Leading Article Open access 30 November 2023 Pages: 101 - 112

28. Cantharidin Topical Solution 0.7%: First Approval

    • Susan J. Keam

    AdisInsight Report 25 November 2023 Pages: 95 - 100

    

29. Prophylactic Intravenous Acetaminophen in Extremely Premature Infants: Minimum Effective Dose Research by Bayesian Approach

    • Naïm Bouazza
    • Gilles Cambonie
    • Jean-Christophe Roze

    Original Research Article Open access 17 November 2023 Pages: 83 - 93

    

30. Emerging Treatments for Childhood Interstitial Lung Disease

    • Nicol Bernardinello
    • Matthias Griese
    • Paolo Spagnolo

    Leading Article Open access 10 November 2023 Pages: 19 - 30

    

31. Practical Questions About Rescue Medications for Acute Treatment of Seizure Clusters in Children and Adolescents with Epilepsy in the USA: Expanding Treatment Options to Address Unmet Needs

    • James W. Wheless
    • Barry Gidal
    • Enrique Carrazana

    Review Article Open access 30 October 2023 Pages: 49 - 57

    

32. Correction to: Viloxazine: Pediatric First Approval

    • Yvette N. Lamb

    Correction Open access 20 October 2023 Pages: 735 - 735

33. Topical Management of Pediatric Psoriasis: A Review of New Developments and Existing Therapies

    • Erina Lie
    • Mira Choi
    • Lawrence F. Eichenfield

    Leading Article Open access 17 October 2023 Pages: 9 - 18

34. Pediatric Drugs, Accelerated Approval, and Prospects for Reform

    • Jeromie Ballreich
    • Hyung-Seok Kim
    • Mariana Socal

    Commentary 14 October 2023 Pages: 5 - 8

35. Respiratory Syncytial Virus Prefusion F Subunit Vaccine: First Approval of a Maternal Vaccine to Protect Infants

    • Yahiya Y. Syed

    AdisInsight Report 13 October 2023 Pages: 729 - 734

    

36. Diagnosis and Management of Non-Infectious Uveitis in Pediatric Patients

    • Ai Tien Nguyen
    • Isabelle Koné-Paut
    • Perrine Dusser

    Review Article 04 October 2023 Pages: 31 - 47

    

37. Diagnosis and Management of the Systemic Juvenile Idiopathic Arthritis Patient with Emerging Lung Disease

    • Christopher Towe
    • Alexei A. Grom
    • Grant S. Schulert

    Leading Article 03 October 2023 Pages: 649 - 658

    

38. Hidradenitis Suppurativa in Children and Adolescents: An Update on Pharmacologic Treatment Options

    • Nicholas Chiang
    • Cathryn Sibbald
    • Irene Lara-Corrales

    Review Article 02 October 2023 Pages: 659 - 676

    

39. Scope of JAK Inhibitors in Children: Recent Evidence and Way Forward

    • Narendra Kumar Bagri
    • Christine Chew
    • A. V. Ramanan

    Leading Article 29 September 2023 Pages: 635 - 647

    

40. Low-Dose Remifentanil in Preterm Cesarean Section with General Anesthesia: A Randomized Controlled Trial

    • Clément Chollat
    • Fabien Tourrel
    • Vincent Compère

    Original Research Article 15 September 2023 Pages: 71 - 81

    

41. Azacitidine (Vidaza^®) in Pediatric Patients with Relapsed Advanced MDS and JMML: Results of a Phase I/II Study by the ITCC Consortium and the EWOG-MDS Group (Study ITCC-015)

    • Alba Rubio-San-Simón
    • Natasha K. A. van Eijkelenburg
    • Christian M. Zwaan

    Original Research Article 11 September 2023 Pages: 719 - 728

    

42. Developments in the Management of Severe Asthma in Children and Adolescents: Focus on Dupilumab and Tezepelumab

    • Yoni E. van Dijk
    • Niels W. Rutjes
    • Susanne J. H. Vijverberg

    Review Article Open access 02 September 2023 Pages: 677 - 693

    

43. Pharmacotherapy for Cancer Treatment-Related Cardiac Dysfunction and Heart Failure in Childhood Cancer Survivors

    • Bibhuti Das

    Review Article 28 August 2023 Pages: 695 - 707

    

44. The Future of Advanced Therapies for Pediatric Crohn’s Disease

    • Julie Gallagher
    • Joel R. Rosh
    • Benjamin Sahn

    Leading Article 23 August 2023 Pages: 621 - 633

45. Impact of Dexmedetomidine Infusion on Opioid and Benzodiazepine Doses in Ventilated Pediatric Patients in the Cardiac Intensive Care Unit

    • Reuth Nir
    • Francesca Sperotto
    • John N. Kheir

    Original Research Article 07 August 2023 Pages: 709 - 718

    

46. Fetal, Preterm, and Term Neonate Exposure to Remifentanil: A Systematic Review of Efficacy and Safety

    • Arielle Maroni
    • Marie-Stéphanie Aubelle
    • Clément Chollat

    Systematic Review 04 August 2023 Pages: 537 - 555

    

47. Effectiveness and Safety of Ustekinumab for Pediatric Inflammatory Bowel Disease: A Systematic Review

    • Shengbo Fang
    • Sixi Zhang
    • Libo Wang

    Systematic Review 01 August 2023 Pages: 499 - 513

    

48. Golimumab in Children with Chronic Recurrent Multifocal Osteomyelitis: A Case Series and Review of the Literature

    • Claire Yang
    • Natalie Rosenwasser
    • Yongdong Zhao

    Original Research Article 21 July 2023 Pages: 603 - 611

    

49. A Review of Histamine-2 Receptor Antagonist and Proton Pump Inhibitor Therapy for Gastroesophageal Reflux Disease in Neonates and Infants

    • Jason Tan
    • Sonia Jeffries
    • Roxane Carr

    Review Article 17 July 2023 Pages: 557 - 576

50. Pharmacokinetics of Commonly Used Antimicrobials in Critically Ill Pediatric Patients During Extracorporeal Membrane Oxygenation: A Systematic Review

    • Marc-Alexandre Duceppe
    • Salmaan Kanji
    • David R. Williamson

    Systematic Review 14 July 2023 Pages: 515 - 535