1. From the Editor

   • Stephen G. Coleman

   EditorialNotes 14 December 2012 Pages: 393 - 394

2. Risks Versus Benefits of Withdrawing Antihypertensive Therapy

   • Hans P. Schobel
   • Roland E. Schmieder
   • Franz H. Messerli

   Leading Article 14 December 2012 Pages: 395 - 403

3. Protein Calorie Malnutrition and Cancer Therapy

   • Howard L. Parnes
   • Joseph Aisner

   Commentary 14 December 2012 Pages: 404 - 416

4. Clinical Toxicity of Interleukin-2

   • Thierry Vial
   • Jacques Descotes

   Drug Experience 14 December 2012 Pages: 417 - 433

5. Adverse Effects of General Anaesthetics

   • Mireille C. Berthoud
   • Charles S. Reilly

   Drug Experience 14 December 2012 Pages: 434 - 459

6. Neuropsychiatric Reactions to Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)

   • David W. J. Clark
   • Karabi Ghose

   Original Research Article 14 December 2012 Pages: 460 - 465