Semi-physiological Pharmacokinetic Model of Clozapine and Norclozapine in Healthy, Non-smoking Volunteers: The Impact of Race and Genetics Orwa AlbitarSabariah Noor HarunSiti Maisharah Sheikh Ghadzi Original Research Article 05 June 2024 Pages: 571 - 581
A Framework for the Administration of Anti-amyloid Monoclonal Antibody Treatments in Early-Stage Alzheimer’s Disease Michael H. RosenbloomTricia O’DonohueThomas J. Grabowski Therapy in Practice Open access 05 June 2024 Pages: 493 - 505
Targeting Biometals in Alzheimer’s Disease with Metal Chelating Agents Including Coumarin Derivatives Adrián GuckýSlávka Hamuľaková Review Article Open access 03 June 2024 Pages: 507 - 532
Intervening in the Premonitory Phase to Prevent Migraine: Prospects for Pharmacotherapy Nazia KarsanPeter J. Goadsby Review Article 31 May 2024 Pages: 533 - 546
Effectiveness of Anti-Calcitonin Gene-Related Peptide Medication in Vestibular Migraine: A Retrospective Cohort Study in an Asian Population Teppei KougaToru MiwaYoshiaki Itoh Original Research Article 29 May 2024
Sex Differences in the Dual Antiplatelet Therapy Versus Alteplase for Patients with Minor Nondisabling Acute Ischemic Stroke: A Secondary Analysis of the ARAMIS Study Hui-Ling QuXiao-Yu SunHui-Sheng Chen Original Research Article 28 May 2024
FcRn Inhibitor Therapies in Neurologic Diseases Nouf AlfaidiSalama KarmastajiVera Bril Review Article 09 May 2024 Pages: 425 - 441
Sex Differences Between Female and Male Individuals in Antipsychotic Efficacy and Adverse Effects in the Treatment of Schizophrenia Megan GalballyKaren WynterSusanna Every-Palmer Original Research Article Open access 07 May 2024 Pages: 559 - 570
Sex Differences in Adverse Effects of Antiseizure Medications in Adults with Epilepsy: A Systematic Review Loretta GiulianoVania Durantethe Epilepsy, Gender Commission of the LICE (Italian chapter of the ILAE) Systematic Review 30 April 2024 Pages: 409 - 423
Post-COVID Trajectory of Pentraxin 3 Plasma Levels Over 6 Months and Their Association with the Risk of Developing Post-Acute Depression and Anxiety Rebecca De LorenzoMario G. MazzaAngelo A. Manfredi Original Research Article 24 April 2024 Pages: 459 - 472
Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data Hasan Çağın LenkRobert Løvsletten SmithEspen Molden Original Research Article Open access 18 April 2024 Pages: 473 - 480
Ticagrelor Versus Clopidogrel in Acute Large-Vessel Ischemic Stroke: A Randomized Controlled Single-Blinded Trial Mohamed G. ZeinhomAhmed ElbassiounySherihan Rezk Ahmed Original Research Article Open access 15 April 2024 Pages: 387 - 398
Impulse Control Disorders in Parkinson’s Disease: An Overview of Risk Factors, Pathogenesis and Pharmacological Management Federico CarboneAtbin Djamshidian Current Opinion Open access 13 April 2024 Pages: 443 - 457
Oral Delta-9-Tetrahydrocannabinol (THC) Increases Parasympathetic Activity and Supraspinal Conditioned Pain Modulation in Chronic Neuropathic Pain Male Patients: A Crossover, Double-Blind, Placebo-Controlled Trial Libat WeizmanHaggai SharonGiris Jacob Original Research Article Open access 10 April 2024 Pages: 375 - 385
On the Optimal Diagnosis and the Evolving Role of Pimavanserin in Parkinson’s Disease Psychosis Fernando L. PaganPaul E. SchulzGregory M. Pontone Therapy in Practice Open access 08 April 2024 Pages: 333 - 347
Synergism of Anti-CGRP Monoclonal Antibodies and OnabotulinumtoxinA in the Treatment of Chronic Migraine: A Real-World Retrospective Chart Review Amira SalimElise HennessyIgnacio F. Mata Original Research Article Open access 07 April 2024 Pages: 481 - 491
CNS Viral Infections—What to Consider for Improving Drug Treatment: A Plea for Using Mathematical Modeling Approaches Ming SunMartijn L. MansonElizabeth C. M. de Lange Review Article Open access 05 April 2024 Pages: 349 - 373
Observation on the Analgesic Effect of Different Doses of a Combination of Esketamine and Dexmedetomidine Administered for Percutaneous Endoscopic Transforaminal Discectomy: A Randomized, Double-Blind Controlled Trial Jian-Shun ZhouZhen ChenLi-Feng Wang Original Research Article 04 April 2024 Pages: 547 - 558
The Gut Microbiota in Parkinson Disease: Interactions with Drugs and Potential for Therapeutic Applications Elisa MenozziAnthony H. V. Schapira Leading Article Open access 03 April 2024 Pages: 315 - 331
The Effect of Levetiracetam Compared with Enzyme-Inducing Antiseizure Medications on Apixaban and Rivaroxaban Peak Plasma Concentrations Rachel GoldsteinNatalie RabkinMordechai Muszkat Original Research Article Open access 23 March 2024 Pages: 399 - 408
An Evidence-Based Update on Anticholinergic Use for Drug-Induced Movement Disorders Nora Vanegas-ArroyaveStanley N. CaroffSamantha A. Cicero Current Opinion Open access 19 March 2024 Pages: 239 - 254
Attention-Deficit Hyperactivity Disorder (ADHD) Medication Use Trajectories Among Women in the Perinatal Period Kathrine Bang MadsenMette BliddalXiaoqin Liu Original Research Article Open access 15 March 2024 Pages: 303 - 314
Magnetic Resonance Imaging Evidence Supporting the Efficacy of Cladribine Tablets in the Treatment of Relapsing-Remitting Multiple Sclerosis Rosa CorteseGiovanna TestaNicola De Stefano Review Article Open access 15 March 2024 Pages: 267 - 279
Current Understanding of Compulsive Sexual Behavior Disorder and Co-occurring Conditions: What Clinicians Should Know about Pharmacological Options Gemma Mestre-BachMarc N. Potenza Review Article 14 March 2024 Pages: 255 - 265
Comparative Efficacy and Safety of Monoclonal Antibodies for Cognitive Decline in Patients with Alzheimer’s Disease: A Systematic Review and Network Meta-Analysis Yue QiaoJian GuYing Ma Systematic Review 01 March 2024 Pages: 169 - 192
The Dose-Response Relationship between Opioid Agonist Therapy and Alterations in Pain Pathways in Patients with Opioid Use Disorders: A Cross-Sectional Study Kordula Lang-IllievichJohanna LangHelmar Bornemann-Cimenti Original Research Article Open access 29 February 2024 Pages: 281 - 290
Pharmacological and Non-pharmacological Approaches for the Management of Neuropathic Pain in Multiple Sclerosis Anastasiia D. ShkodinaMainak BardhanMykhailo Yu. Delva Review Article 29 February 2024 Pages: 205 - 224
Real-World Retrospective Analysis of Alemtuzumab Outcomes in Relapsing-Remitting Multiple Sclerosis: The LEMCAM Study Lucienne Costa-Frossard FrançaVirginia Meca LallanaJosé Manuel García Domínguez Original Research Article Open access 28 February 2024 Pages: 231 - 238
SAFE-ROCK: A Phase I Trial of an Oral Application of the ROCK Inhibitor Fasudil to Assess Bioavailability, Safety, and Tolerability in Healthy Participants Andreas W. WolffJörg PeinePaul Lingor Original Research Article Open access 28 February 2024 Pages: 291 - 302
Andexanet Alfa: What We Have Learned from Clinical Trials and Real-World Data Senta FrolJanja Pretnar OblakPawel Kermer Current Opinion 23 February 2024 Pages: 163 - 168
Unmet Needs in Psychodermatology: A Narrative Review Rachel E. ChristensenMohammad Jafferany Review Article 22 February 2024 Pages: 193 - 204
Benzodiazepines for the Treatment of Seizure Clusters Patricia E. PenovichVikram R. RaoAdrian L. Rabinowicz Review Article Open access 15 February 2024 Pages: 125 - 140
Targeting Pannexin-1 Channels: Addressing the ‘Gap’ in Chronic Pain Brendan B. McAllisterSierra Stokes-HeckTuan Trang Leading Article 14 February 2024 Pages: 77 - 91
The Efficacy and Safety of Different Targeted Drugs for the Treatment of Generalized Myasthenia Gravis: A Systematic Review and Bayesian Network Meta-analysis Yongbo MaXiangtao NieXiuming Guo Systematic Review 01 February 2024 Pages: 93 - 104
Trends in Pregabalin Use and Prescribing Patterns in the Adult Population: A 10-Year Pharmacoepidemiologic Study Nofar Benassayag KaduriReuven DresslerVictoria Rotshild Original Research Article Open access 25 January 2024 Pages: 153 - 162
Early Experiences with Intrathecal Administration of Amphotericin B Liposomal Formulation at a Neurosurgical Center Michael D. NailorKellie J. GoodletJ. Tyler Haller Original Research 25 January 2024 Pages: 225 - 229
Effect of Cenobamate on Cognition in Patients with Drug-Resistant Epilepsy with Focal Onset Seizures: An Exploratory Study Pedro J Serrano-CastroTeresa Ramírez-GarcíaJuan De La Parra Original Research Article Open access 24 January 2024 Pages: 141 - 151
Treatment of Sleep, Motor and Sensory Symptoms with the Orexin Antagonist Suvorexant in Adults with Idiopathic Restless Legs Syndrome: A Randomized Double-Blind Crossover Proof-of-Concept Study Diego Garcia-BorregueroAlba Garcia AragónMaría Castillo Original Research Article 21 January 2024 Pages: 45 - 54
Evaluating Monitoring Guidelines of Clozapine-Induced Adverse Effects: a Systematic Review Sarah SmessaertJohan DetrauxMarc De Hert Systematic Review 18 January 2024 Pages: 105 - 123
Myasthenia Gravis Treatment: From Old Drugs to Innovative Therapies with a Glimpse into the Future Salvatore CrisafulliBrigida BoccanegraAnnamaria De Luca Review Article 11 January 2024 Pages: 15 - 32
Factors Associated with Symptom Stabilization that Allow for Successful Transition from Once-Monthly Paliperidone Palmitate to Three-Monthly Paliperidone Palmitate: A Post Hoc Analysis Examined Clinical Characteristics in Chinese Patients with Schizophrenia Xin LiChong YeGang Wang Original Research Article Open access 08 January 2024 Pages: 55 - 65
Effect of Levetiracetam on Cognition: A Systematic Review and Meta-analysis of Double-Blind Randomized Placebo-Controlled Trials Chia-Yen LinMeng-Chia ChangHong-Jie Jhou Systematic Review 15 December 2023 Pages: 1 - 14
Insulin Resistance/Diabetes and Schizophrenia: Potential Shared Genetic Factors and Implications for Better Management of Patients with Schizophrenia Chuanjun ZhuoQiuyu ZhangDeguo Jiang Review Article Open access 14 December 2023 Pages: 33 - 44
Thrombolysis with Recombinant Human Prourokinase 4.5–6 h After Acute Ischemic Stroke: A Phase IIa, Randomized, and Open-Label Multicenter Clinical Trial Haiqing SongYuan WangYuping Wang Original Research Article Open access 29 November 2023 Pages: 67 - 75
Effect of BI 1358894 on Cholecystokinin-Tetrapeptide (CCK-4)-Induced Anxiety, Panic Symptoms, and Stress Biomarkers: A Phase I Randomized Trial in Healthy Males Markus GoettelRene FuertigJohan den Boer Original Research Article Open access 29 November 2023 Pages: 1099 - 1109
Effects of Single and Multiple Ascending Doses of BI 1358894 in Healthy Male Volunteers on Safety, Tolerability and Pharmacokinetics: Two Phase I Partially Randomised Studies René FuertigMarkus GoettelVikas Sharma Original Research Article Open access 29 November 2023 Pages: 1081 - 1097
Long-Term Treatment Over 52 Weeks with Monthly Fremanezumab in Drug-Resistant Migraine: A Prospective Multicenter Cohort Study Valeria CaponnettoAntonio RussoThe Italian Headache Registry (RICe) Study Group Original Research Article Open access 24 November 2023 Pages: 1069 - 1080
Context is a Critical for Psychoactive Drug Effects Kyle T. Greenway Commentary 24 November 2023 Pages: 1065 - 1068
The effects of Lysergic Acid Diethylamide (LSD) on the Positive Valence Systems: A Research Domain Criteria (RDoC)-Informed Systematic Review Niloufar PouyanFarnaz Younesi SisiJonathan D. Morrow Systematic Review Open access 24 November 2023 Pages: 1027 - 1063
Levetiracetam Interaction with Direct Oral Anticoagulants: A Pharmacovigilance Study Mohammed Abou KaoudRan NissanElad Maor Original Research Article 22 November 2023 Pages: 1111 - 1121