Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations Carmen WalterClaudia KnotheJörn Lötsch Leading Article 30 December 2015 Pages: 751 - 767
A Comprehensive Review of Novel Drug–Disease Models in Diabetes Drug Development Puneet GaitondeParag GarhyanStephan Schmidt Review Article 21 January 2016 Pages: 769 - 788
Potential Sources of Inter-Subject Variability in Monoclonal Antibody Pharmacokinetics Katherine L. GillKrishna K. MachavaramManoranjenni Chetty Review Article 27 January 2016 Pages: 789 - 805
Pharmacokinetics of Cannabis in Cancer Cachexia-Anorexia Syndrome Stephanie E. ReuterJennifer H. Martin Review Article 16 February 2016 Pages: 807 - 812
Pharmacokinetic/Pharmacodynamic Modelling of Receptor Internalization with CRTH2 Antagonists to Optimize Dose Selection Andreas KrauseJochen ZisowskyJasper Dingemanse Original Research Article 21 December 2015 Pages: 813 - 821
Combining ‘Bottom-Up’ and ‘Top-Down’ Methods to Assess Ethnic Difference in Clearance: Bitopertin as an Example Sheng FengJun ShiRichard Peck Original Research Article Open access 29 December 2015 Pages: 823 - 832
Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen Anne van RongenPyry A. J. VälitaloCatherijne A. J. Knibbe Original Research Article Open access 27 January 2016 Pages: 833 - 847
Propofol Breath Monitoring as a Potential Tool to Improve the Prediction of Intraoperative Plasma Concentrations Pieter ColinDouglas J. EleveldCyrill Hornuss Original Research Article 29 December 2015 Pages: 849 - 859
Comprehensive Pharmacokinetic, Pharmacodynamic and Pharmacogenetic Evaluation of Once-Daily Efavirenz 400 and 600 mg in Treatment-Naïve HIV-Infected Patients at 96 Weeks: Results of the ENCORE1 Study Laura DickinsonJanaki AminRebekah Puls Original Research Article Open access 29 December 2015 Pages: 861 - 873
Clinical Micro-Dose Studies to Explore the Human Pharmacokinetics of Four Selective Inhibitors of Human Nav1.7 Voltage-Dependent Sodium Channels Hannah M. JonesRichard P. ButtKevin Beaumont Original Research Article 19 February 2016 Pages: 875 - 887
Single- and Multiple-Dose Milnacipran Pharmacokinetics in Healthy Han Chinese Volunteers Can-Jun RuanAn-Ning LiJose de Leon Short Communication 10 December 2015 Pages: 889 - 896