1. To Apply Microdosing or Not? Recommendations to Single Out Compounds with Non-Linear Pharmacokinetics

   • Sieto Bosgra
   • Maria L. H. Vlaming
   • Wouter H. J. Vaes

   Leading Article 05 August 2015 Pages: 1 - 15

   

2. A Critical Review of the Current Evidence for Measuring Drug Concentrations of First-Line Agents Used to Treat Tuberculosis in Children

   • Kyle John Wilby
   • Sara Shabana
   • Fawziah Marra

   Review Article 16 July 2015 Pages: 17 - 31

3. Clinical Pharmacokinetic and Pharmacodynamic Profile of Idelalisib

   • Srinivasan Ramanathan
   • Feng Jin
   • Brian P. Kearney

   Review Article 05 August 2015 Pages: 33 - 45

   

4. Pharmacokinetic Aspects of Vascular Endothelial Growth Factor Tyrosine Kinase Inhibitors

   • Beatrix Wulkersdorfer
   • Markus Zeitlinger
   • Monika Schmid

   Review Article 23 July 2015 Pages: 47 - 77

5. Effects of Cytochrome P450 Inhibition and Induction on the Phenotyping Metrics of the Basel Cocktail: A Randomized Crossover Study

   • Adrian Derungs
   • Massimiliano Donzelli
   • Manuel Haschke

   Original Research Article Open access 28 June 2015 Pages: 79 - 91

   

6. Population Pharmacokinetic Model of Cabozantinib in Patients with Medullary Thyroid Carcinoma and Its Application to an Exposure-Response Analysis

   • Dale Miles
   • Nelson L. Jumbe
   • Linh Nguyen

   Original Research Article 07 July 2015 Pages: 93 - 105

   

7. Population Pharmacokinetics of Intravenous Paracetamol (Acetaminophen) in Preterm and Term Neonates: Model Development and External Evaluation

   • Sarah F. Cook
   • Jessica K. Roberts
   • John N. van den Anker

   Original Research Article 23 July 2015 Pages: 107 - 119

   

8. Blockade of the High-Affinity Interleukin-2 Receptors with Daclizumab High-Yield Process: Pharmacokinetic/Pharmacodynamic Analysis of Single- and Multiple-Dose Phase I Trials

   • Mukul Minocha
   • Jonathan Q. Tran
   • Ahmed A. Othman

   Original Research Article 05 August 2015 Pages: 121 - 130

   

9. Comment on: “Enzalutamide: A Step Towards Pharmacokinetic-Based Dosing in Men with Metastatic Castration-Resistant Prostate Cancer”

   • Jacqueline A. Gibbons

   Letter to the Editor Open access 09 December 2015 Pages: 131 - 132

10. Comment on: “A Physiologically Based Pharmacokinetic Drug-Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by Incorporating Pathophysiological Changes in Hepatic and Renal Blood”

    • Guo-Fu Li
    • Xiao Gu
    • Qing-Shan Zheng

    Letter to the Editor 09 December 2015 Pages: 133 - 137

11. Author’s Reply to Zheng et al.: A Physiologically Based Pharmacokinetic Drug–Disease Model to Predict Carvedilol Exposure in Adult and Paediatric Heart Failure Patients by Incorporating Pathophysiological Changes in Hepatic and Renal Blood Flows

    • Muhammad Fawad Rasool
    • Feras Khalil
    • Stephanie Läer

    Letter to the Editor 09 December 2015 Pages: 139 - 141