Neuronal STING activation in amyotrophic lateral sclerosis and frontotemporal dementia Christine MarquesAaron HeldBrian J. Wainger Original Paper Open access 13 March 2024 Article: 56
MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons Hong XuQi QiuVirginia M.-Y. Lee Original Paper Open access 12 March 2024 Article: 55
Role of GBA variants in Lewy body disease neuropathology Ronald L. WaltonShunsuke KogaMichael G. Heckman Original Paper 12 March 2024 Article: 54
Alteration of LARGE1 abundance in patients and a mouse model of 5q-associated spinal muscular atrophy Andreas RoosLinda-Isabell SchmittTim Hagenacker Original Paper Open access 12 March 2024 Article: 53
Comprehensive proteomics of CSF, plasma, and urine identify DDC and other biomarkers of early Parkinson’s disease Jarod RutledgeBenoit LehallierKathleen L. Poston Original Paper Open access 11 March 2024 Article: 52
The prevalence and topography of spinal cord demyelination in multiple sclerosis: a retrospective study Alex D. WaldmanCecilia CataniaGabriele C. DeLuca Original Paper Open access 09 March 2024 Article: 51
RNA aptamer reveals nuclear TDP-43 pathology is an early aggregation event that coincides with STMN-2 cryptic splicing and precedes clinical manifestation in ALS Holly SpenceFergal M. WaldronJenna M. Gregory Original Paper Open access 05 March 2024 Article: 50
Methylation class oligosarcoma, IDH-mutant could exhibit astrocytoma-like molecular features Lingyu LiuYuqing LiuKe-Nan Zhang Correspondence 05 March 2024 Article: 49
Astroglial calcium signaling and homeostasis in tuberous sclerosis complex Alessia RomagnoloGiulia DematteisEleonora Aronica Original Paper Open access 28 February 2024 Article: 48
Disruption of the blood–brain barrier is correlated with spike endocytosis by ACE2 + endothelia in the CNS microvasculature in fatal COVID-19. Scientific commentary on "Detection of blood–brain barrier disruption in brains of patients with COVID-19, but no evidence of brain penetration by SARS-CoV-2” Cynthia MagroEsmerina TiliGerard Nuovo Correspondence 27 February 2024 Article: 47
Myofiber-type-dependent ‘boulder’ or ‘multitudinous pebble’ formations across distinct amylopectinoses Sharmistha MitraBaozhi ChenBerge A. Minassian Original Paper 27 February 2024 Article: 46
Cortical-sparing chronic traumatic encephalopathy (CSCTE): a distinct subtype of CTE Abigail AlexanderVictor E. AlvarezThor D. Stein Original Paper 26 February 2024 Article: 45
MET receptor serves as a promising target in melanoma brain metastases Torben RedmerElisa SchumannJosefine Radke Original Paper Open access 22 February 2024 Article: 44
Canine meningiomas are comprised of 3 DNA methylation groups that resemble the molecular characteristics of human meningiomas Naomi ZakimiChristina N. MazckoDavid R. Raleigh Correspondence Open access 20 February 2024 Article: 43
Aggressive human MenG C meningiomas have a molecular counterpart in canines Akdes S. HarmanciBeth BoudreauAkash J. Patel Correspondence 20 February 2024 Article: 42
PP2A and GSK3 act as modifiers of FUS-ALS by modulating mitochondrial transport Paraskevi TziortzoudaJolien SteyaertLudo Van Den Bosch Original Paper Open access 16 February 2024 Article: 41
Regional AT-8 reactive tau species correlate with intracellular Aβ levels in cases of low AD neuropathologic change Nauman MalikMohi-Uddin MiahDavid J. Koss Original Paper Open access 14 February 2024 Article: 40
The contribution of β-amyloid, Tau and α-synuclein to blood–brain barrier damage in neurodegenerative disorders Ying-Chieh WuTizibt Ashine BogaleArianna Bellucci Review Open access 12 February 2024 Article: 39
Endothelial cells and macrophages as allies in the healthy and diseased brain Adam DenesCathrin E. HansenMarkus Schwaninger Review Open access 12 February 2024 Article: 38
The niche matters: origin, function and fate of CNS-associated macrophages during health and disease Adrià Dalmau GasullMartina GlavanMarco Prinz Review Open access 12 February 2024 Article: 37
Macrophages and endothelial cells in the neurovascular unit Jan WenzelMarkus Schwaninger Editorial Open access 12 February 2024 Article: 36
Reply: pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion Ramin RahmanzadeFelix Sahm Correspondence Open access 10 February 2024 Article: 35
Pineal parenchymal tumors of intermediate differentiation: in need of a stringent definition to avoid confusion. Scientific commentary on ‘Genetical and epigenetical profiling identifies two subgroups of pineal parenchymal tumors of intermediate differentiation (PPTID) with distinct molecular, histological and clinical characteristics’ Alexandre Vasiljevic Correspondence Open access 10 February 2024 Article: 34
“RYR1 and the cerebellum”: scientific commentary on “Defective Cerebellar Ryanodine Receptor Type 1 and Endoplasmic Reticulum Calcium ‘Leak’ in Tremor Pathophysiology” Heinz JungbluthDennis T. FamiliNicol C. Voermans Correspondence Open access 07 February 2024 Article: 33
Transmembrane protein 97 is a potential synaptic amyloid beta receptor in human Alzheimer’s disease Martí Colom-CadenaJamie ToombsTara L. Spires-Jones Original Paper Open access 06 February 2024 Article: 32
New insights into neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis Yong GuoVerena EndmayrRomana Höftberger Original Paper Open access 03 February 2024 Article: 31
Scientific commentary on: “Phosphorylated tau in the retina correlates with tau pathology in the brain in Alzheimer’s disease and primary tauopathies” Frederike C. OertelDaniel CasillasAri J. Green Correspondence Open access 03 February 2024 Article: 30
Cryptic exon inclusion is a molecular signature of LATE-NC in aging brains Mingee ChungE. Kathleen CarterZachary T. McEachin Original Paper Open access 03 February 2024 Article: 29
Neuroinflammatory disease signatures in SPG11-related hereditary spastic paraplegia patients Laura KrummTatyana PoznerMartin Regensburger Original Paper Open access 02 February 2024 Article: 28
Similar brain proteomic signatures in Alzheimer’s disease and epilepsy Dominique LeitnerGeoffrey PiresEleanor Drummond Original Paper Open access 30 January 2024 Article: 27
Mitochondrial damage and impaired mitophagy contribute to disease progression in SCA6 Tsz Chui Sophia LeungEviatar FieldsAlanna J. Watt Original Paper Open access 29 January 2024 Article: 26
Head-to-head comparison of [18F]-Flortaucipir, [18F]-MK-6240 and [18F]-PI-2620 postmortem binding across the spectrum of neurodegenerative diseases Cinthya AgueroMaeva DhaynautTeresa Gómez-Isla Original Paper Open access 27 January 2024 Article: 25
Molecular characteristics and improved survival prediction in a cohort of 2023 ependymomas Lara C. PohlMaximilian LeitheiserUlrich Schüller Original Paper Open access 24 January 2024 Article: 24
Clinically relevant molecular hallmarks of PFA ependymomas display intratumoral heterogeneity and correlate with tumor morphology Swenja GödickeCatena KresbachUlrich Schüller Original Paper Open access 24 January 2024 Article: 23
Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation Sina NeyaziErika YamazawaUlrich Schüller Original Paper Open access 24 January 2024 Article: 22
Temporal change of DNA methylation subclasses between matched newly diagnosed and recurrent glioblastoma Richard DrexlerRobin KhatriFranz L. Ricklefs Original Paper Open access 20 January 2024 Article: 21
A familial missense variant in the Alzheimer’s disease gene SORL1 impairs its maturation and endosomal sorting Elnaz FazeliDaniel D. ChildJessica E. Young Original Paper Open access 20 January 2024 Article: 20
Multi-level profiling unravels mitochondrial dysfunction in myotonic dystrophy type 2 Felix KleefeldRita HorvathWerner Stenzel Original Paper Open access 19 January 2024 Article: 19
Performance of a seed amplification assay for misfolded alpha-synuclein in cerebrospinal fluid and brain tissue in relation to Lewy body disease stage and pathology burden Giuseppe Mario BentivengaAngela MammanaPiero Parchi Original Paper Open access 19 January 2024 Article: 18
Large-scale validation of skin prion seeding activity as a biomarker for diagnosis of prion diseases Weiguanliu ZhangChristina D. OrrúWen-Quan Zou Original Paper 17 January 2024 Article: 17
Pituitary neuroendocrine tumors with PIT1/SF1 co-expression show distinct clinicopathological and molecular features Matthias DottermuschAlice RybaUlrich Schüller Original Paper Open access 16 January 2024 Article: 16
Complement and MHC patterns can provide the diagnostic framework for inflammatory neuromuscular diseases Christopher NelkeSimone SchmidWerner Stenzel Review Open access 12 January 2024 Article: 15
Distinct tau and alpha-synuclein molecular signatures in Alzheimer’s disease with and without Lewy bodies and Parkinson’s disease with dementia Bram L. van der GaagNatasja A. C. DeshayesWilma D. J. van de Berg Original Paper Open access 10 January 2024 Article: 14
Novel lissencephaly-associated NDEL1 variant reveals distinct roles of NDE1 and NDEL1 in nucleokinesis and human cortical malformations Meng-Han TsaiHao-Chen KeJin-Wu Tsai Original Paper Open access 09 January 2024 Article: 13
CSF p-tau205: a biomarker of tau pathology in Alzheimer’s disease Juan Lantero-RodriguezLaia Montoliu-GayaKaj Blennow Original Paper Open access 06 January 2024 Article: 12
Improved prognostic stratification of patients with isocitrate dehydrogenase-mutant astrocytoma Michael WellerJörg FelsbergGuido Reifenberger Original Paper Open access 06 January 2024 Article: 11
New evidence suggests SARS-CoV-2 neuroinvasion along the nervus terminalis rather than the olfactory pathway Christopher S. von BartheldRafal Butowt Correspondence 06 January 2024 Article: 10
Cryptic splicing of stathmin-2 and UNC13A mRNAs is a pathological hallmark of TDP-43-associated Alzheimer’s disease Ana Rita Agra Almeida QuadrosZhaozhi LiClotilde Lagier-Tourenne Original Paper Open access 04 January 2024 Article: 9
Cortical matrix remodeling as a hallmark of relapsing–remitting neuroinflammation in MR elastography and quantitative MRI Rafaela V. SilvaAnna S. MorrIngolf Sack Original Paper Open access 04 January 2024 Article: 8
p-tau Ser356 is associated with Alzheimer’s disease pathology and is lowered in brain slice cultures using the NUAK inhibitor WZ4003 Lewis W. TaylorElizabeth M. SimzerClaire S. Durrant Original Paper Open access 04 January 2024 Article: 7