1. Tuberous sclerosis complex is associated with a novel human tauopathy

   • Ji-Hye L. Hwang
   • Olga S. Perloff
   • William W. Seeley

   Original Paper 05 December 2022 Pages: 1 - 12

   

2. Widespread CNS pathology in amyotrophic lateral sclerosis homozygous for the D90A SOD1 mutation

   • Karin M. Forsberg
   • Karin S. Graffmo
   • Peter M. Andersen

   Original Paper Open access 16 November 2022 Pages: 13 - 28

   

3. RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

   • Yoon A. Kim
   • Tohid Siddiqui
   • Ismael Santa-Maria

   Original Paper Open access 10 November 2022 Pages: 29 - 48

   

4. Amplification of the PLAG-family genes—PLAGL1 and PLAGL2—is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

   • Michaela-Kristina Keck
   • Martin Sill
   • David T. W. Jones

   Original Paper Open access 27 November 2022 Pages: 49 - 69

   

5. Expanded analysis of high-grade astrocytoma with piloid features identifies an epigenetically and clinically distinct subtype associated with neurofibromatosis type 1

   • Patrick J. Cimino
   • Courtney Ketchum
   • Kenneth Aldape

   Original Paper 22 October 2022 Pages: 71 - 82

   

6. Pediatric spinal pilocytic astrocytomas form a distinct epigenetic subclass from pilocytic astrocytomas of other locations and diffuse leptomeningeal glioneuronal tumours

   • Alice Métais
   • Yassine Bouchoucha
   • Arnault Tauziède-Espariat

   Original Paper Open access 20 October 2022 Pages: 83 - 95

   

7. Identification of low and very high-risk patients with non-WNT/non-SHH medulloblastoma by improved clinico-molecular stratification of the HIT2000 and I-HIT-MED cohorts

   • Martin Mynarek
   • Denise Obrecht
   • Till Milde

   Original Paper Open access 02 December 2022 Pages: 97 - 112

   

8. Neuropathology of central nervous system involvement in TTR amyloidosis

   • Ricardo Taipa
   • Luísa Sousa
   • Teresa Coelho

   Original Paper Open access 06 October 2022 Pages: 113 - 126

   

9. Loss of function variants in DNAJB4 cause a myopathy with early respiratory failure

   • Conrad C. Weihl
   • Ana Töpf
   • Volker Straub

   Original Paper 20 October 2022 Pages: 127 - 143

   

10. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials

    • Nicholas G. Gottardo

    Correspondence Open access 20 November 2022 Pages: 145 - 147

11. NTRK rearrangements in a subset of NF1-related malignant peripheral nerve sheath tumors as novel actionable target

    • L. S. Hiemcke-Jiwa
    • M. T. Meister
    • L. A. Kester

    Correspondence Open access 04 November 2022 Pages: 149 - 152

    

12. Novel actionable ROS1::GIT2 fusion in non-Langerhans cell histiocytosis with central nervous system involvement

    • Gábor Bedics
    • Monika Csóka
    • Bálint Scheich

    Correspondence Open access 23 November 2022 Pages: 153 - 156

    

13. Correction to: Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease

    • YuHong Fu
    • Liche Zhou
    • Glenda M. Halliday

    Correction Open access 27 November 2022 Pages: 157 - 157