1. Strain diversity in neurodegenerative disease: an argument for a personalized medicine approach to diagnosis and treatment

   • Amanda L. Woerman

   Editorial 23 April 2021 Pages: 1 - 3

2. Environmental and host factors that contribute to prion strain evolution

   • Jason C. Bartz

   Review 25 April 2021 Pages: 5 - 16

   

3. The existence of Aβ strains and their potential for driving phenotypic heterogeneity in Alzheimer’s disease

   • Heather H. C. Lau
   • Martin Ingelsson
   • Joel C. Watts

   Review 02 August 2020 Pages: 17 - 39

   

4. Phenotypic diversity in ALS and the role of poly-conformational protein misfolding

   • Jacob I. Ayers
   • David R. Borchelt

   Review 15 September 2020 Pages: 41 - 55

   

5. Tau strains shape disease

   • Jaime Vaquer-Alicea
   • Marc I. Diamond
   • Lukasz A. Joachimiak

   Review Open access 08 April 2021 Pages: 57 - 71

   

6. Evidence of distinct α-synuclein strains underlying disease heterogeneity

   • Sara A. M. Holec
   • Amanda L. Woerman

   Review 21 May 2020 Pages: 73 - 86

   

7. Multiple system atrophy-associated oligodendroglial protein p25α stimulates formation of novel α-synuclein strain with enhanced neurodegenerative potential

   • Nelson Ferreira
   • Hjalte Gram
   • Poul Henning Jensen

   Original Paper Open access 12 May 2021 Pages: 87 - 115

   

8. LRP10 interacts with SORL1 in the intracellular vesicle trafficking pathway in non-neuronal brain cells and localises to Lewy bodies in Parkinson’s disease and dementia with Lewy bodies

   • Martyna M. Grochowska
   • Ana Carreras Mascaro
   • Wim Mandemakers

   Original Paper Open access 28 April 2021 Pages: 117 - 137

   

9. ApoE4 inhibition of VMAT2 in the locus coeruleus exacerbates Tau pathology in Alzheimer’s disease

   • Seong Su Kang
   • Eun Hee Ahn
   • Keqiang Ye

   Original Paper 25 April 2021 Pages: 139 - 158

   

10. A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer’s disease

    • Vega García-Escudero
    • Daniel Ruiz-Gabarre
    • Jesús Ávila

    Original Paper Open access 02 May 2021 Pages: 159 - 177

    

11. Glioblastomas with primitive neuronal component harbor a distinct methylation and copy-number profile with inactivation of TP53, PTEN, and RB1

    • Abigail K. Suwala
    • Damian Stichel
    • Felix Sahm

    Original Paper Open access 19 April 2021 Pages: 179 - 189

    

12. Rare germline variants in the E-cadherin gene CDH1 are associated with the risk of brain tumors of neuroepithelial and epithelial origin

    • Alisa Förster
    • Frank Brand
    • Ruthild G. Weber

    Original Paper Open access 30 April 2021 Pages: 191 - 210

    

13. Alzheimer’s disease neuropathological change three decades after iatrogenic amyloid-β transmission

    • Zane Jaunmuktane
    • Gargi Banerjee
    • Sebastian Brandner

    Correspondence Open access 28 May 2021 Pages: 211 - 215

    

14. TBK1 haploinsufficiency in ALS and FTD compromises membrane trafficking

    • Yubing Lu
    • Sandra Almeida
    • Fen-Biao Gao

    Correspondence 03 June 2021 Pages: 217 - 221

    

15. Correction to: Large‑scale pathway specific polygenic risk and transcriptomic community network analysis identifies novel functional pathways in Parkinson disease

    • S. Bandres-Ciga
    • S. Saez-Atienzar
    • the International Parkinson Disease Genomics Consortium

    Correction Open access 04 May 2021 Pages: 223 - 224

16. Correction to: Transmissible α‑synuclein seeding activity in brain and stomach of patients with Parkinson’s disease

    • Achim Thomzig
    • Katja Wagenführ
    • Michael Beekes

    Correction Open access 06 May 2021 Pages: 225 - 225