Role of chemotherapy in the treatment of metastatic castration-resistant prostate cancer patients who have progressed after abiraterone acetate Roberto PetrioliEdoardo FranciniGiandomenico Roviello Review Article 17 June 2015 Pages: 439 - 445
Reproductive hormone levels and differential mitochondria-related oxidative gene expression as potential mechanisms for gender differences in cardiosensitivity to Doxorubicin in tumor-bearing spontaneously hypertensive rats Yanira GonzalezKaytee L. PokrzywinskiV. Ashutosh Rao Original Article 25 June 2015 Pages: 447 - 459
AT-101 inhibits hedgehog pathway activity and cancer growth Juan WangYuanqiu PengWenfu Tan Original Article 26 June 2015 Pages: 461 - 469
NECTIN-4 increased the 5-FU resistance in colon cancer cells by inducing the PI3K–AKT cascade Dipon DasShakti Ranjan SatapathyChanakya Nath Kundu Original Article 30 June 2015 Pages: 471 - 479
Phase I study of combination of pasireotide LAR + gemcitabine in locally advanced or metastatic pancreatic cancer Yaman SuleimanAmit MahipalRichard Kim Original Article 01 July 2015 Pages: 481 - 487
Family history as a marker of platinum sensitivity in pancreatic adenocarcinoma David FogelmanElizabeth A. SugarLuis A. Diaz Jr. Original Article 01 July 2015 Pages: 489 - 498
Safety of topotecan monotherapy for relapsed small cell lung cancer patients with pre-existing interstitial lung disease Yasunori EnomotoNaoki InuiTakafumi Suda Original Article 02 July 2015 Pages: 499 - 505
Integrated nonclinical and clinical risk assessment of the investigational proteasome inhibitor ixazomib on the QTc interval in cancer patients Neeraj GuptaYeamin HuhKarthik Venkatakrishnan Original Article 04 July 2015 Pages: 507 - 516
A phase II study of icotinib and whole-brain radiotherapy in Chinese patients with brain metastases from non-small cell lung cancer Yun FanZhiyu HuangWeimin Mao Original Article 07 July 2015 Pages: 517 - 523
In vivo pharmacokinetic and tissue distribution investigation of sustained-release cisplatin implants in the normal esophageal submucosa of 12 beagle dogs Jia-Xue YinZhi WeiZi-Qin Sun Original Article 17 July 2015 Pages: 525 - 536
Characterization of the metabolism of benzaldehyde dimethane sulfonate (NSC 281612, DMS612) Robert A. PariseJulie L. EisemanJan H. Beumer Original Article 21 July 2015 Pages: 537 - 546
A phase II study of S-1, oxaliplatin, oral leucovorin, and bevacizumab combination therapy (SOLA) in patients with unresectable metastatic colorectal cancer Tomohiro NishinaTakeshi KatoIchinosuke Hyodo Original Article 22 July 2015 Pages: 547 - 553
Lower antioxidative capacity of multidrug-resistant cancer cells confers collateral sensitivity to protoflavone derivatives Tijana StankovićBalázs DankóMilica Pešić Original Article 22 July 2015 Pages: 555 - 565
Modeling and simulations relating overall survival to tumor growth inhibition in renal cell carcinoma patients Laurent ClaretFrancois MercierRene Bruno Original Article 22 July 2015 Pages: 567 - 573
Gossypol sensitizes the antitumor activity of 5-FU through down-regulation of thymidylate synthase in human colon carcinoma cells Dan YangJinglei QuYunpeng Liu Original Article 25 July 2015 Pages: 575 - 586
Clinical pharmacology characterization of RG7112, an MDM2 antagonist, in patients with advanced solid tumors Amita PatnaikAnthony TolcherJianguo Zhi Original Article 26 July 2015 Pages: 587 - 595
A phase 1 study of intermittently administered pazopanib in combination with continuous daily dosing of lapatinib in patients with solid tumors H. HenaryG. C. GeorgeD. S. Hong Original Article 26 July 2015 Pages: 597 - 603
S-1 and irinotecan with or without bevacizumab versus 5-fluorouracil and leucovorin plus oxaliplatin with or without bevacizumab in metastatic colorectal cancer: a pooled analysis of four phase II studies Satoru IwasaKengo NagashimaYasuhide Yamada Original Article 29 July 2015 Pages: 605 - 614
A phase I/II study of fixed-dose-rate gemcitabine and S-1 with concurrent radiotherapy for locally advanced pancreatic cancer Takahiro GojiTetsuo KimuraTetsuji Takayama Original Article 29 July 2015 Pages: 615 - 620
Predictive value of STMN1 gene promoter polymorphism (−2166T>C) in patients with advanced NSCLC treated with the combination of platinum compounds and vinorelbine Radosław MlakPaweł KrawczykTeresa Małecka-Massalska Original Article Open access 29 July 2015 Pages: 621 - 629
A Phase I study of MEDI-575, a PDGFRα monoclonal antibody, in Japanese patients with advanced solid tumors Haruyasu MurakamiMasafumi IkedaNobuyuki Yamamoto Original Article 30 July 2015 Pages: 631 - 639
Inhibition of ovarian cancer cell growth by a novel TAK1 inhibitor LYTAK1 Liu YingYin ChunxiaLiu Wei Original Article 31 July 2015 Pages: 641 - 650
Cisplatin-based chronotherapy for advanced non-small cell lung cancer patients: a randomized controlled study and its pharmacokinetics analysis Jie LiRong ChenLi-na Zhu Clinical Trial Report 21 June 2015 Pages: 651 - 655
RETRACTED ARTICLE: ABCB1 (1199G>A) polymorphism regulates the efficacy of docetaxel and imatinib mesylate in HEK293 recombinant cell lines Rui PengHong ZhangDan-yun Wei Original Article Open access 21 June 2015 Pages: 657 - 657