Combined cytotoxic action of paclitaxel and ceramide against the human Tu138 head and neck squamous carcinoma cell line Shashi MehtaDilshad BlackintonHarold Wanebo ORIGINAL ARTICLE Pages: 85 - 92
Interaction of dexrazoxane with red blood cells and hemoglobin alters pharmacokinetics of doxorubicin Sujata VaidyanathanMehdi Boroujerdi ORIGINAL ARTICLE Pages: 93 - 100
F 11782, a dual inhibitor of topoisomerases I and II with an original mechanism of action in vitro, and markedly superior in vivo antitumour activity, relative to three other dual topoisomerase inhibitors, intoplicin, aclarubicin and TAS-103 Chantal EtiévantAnna KruczynskiBridget T. Hill ORIGINAL ARTICLE Pages: 101 - 113
Retrospective comparison of toxicity and efficacy in phase II trials of 3-h infusions of paclitaxel for patients 70 years of age or older and patients under 70 years of age Yoichi NakamuraIkuo SekineNagahiro Saijo ORIGINAL ARTICLE Pages: 114 - 118
Reduction of cyclophosphamide bioactivation by thioTEPA: critical sequence-dependency in high-dose chemotherapy regimens Alwin D. R. HuitemaThomas KerbuschJos H. Beijnen ORIGINAL ARTICLE Pages: 119 - 127
Differences in uptake and metabolism of retinoic acid between estrogen receptor-positive and -negative human breast cancer cells Kosuke OkamotoFausto AndreolaLuigi M. De Luca ORIGINAL ARTICLE Pages: 128 - 134
Modulation of the pharmacokinetics of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in mice by thalidomide Philip KestellLiangli ZhaoLai-Ming Ching ORIGINAL ARTICLE Pages: 135 - 141
Antitumor activity of cryptophycins: effect of infusion time and combination studies Krishna MenonEnrique AlvarezBeverly A. Teicher ORIGINAL ARTICLE Pages: 142 - 149
Pharmacokinetics of oral O6-benzylguanine and evidence of interaction with oral ketoconazole in the rat Reginald B. EwesuedoM. Eileen Dolan ORIGINAL ARTICLE Pages: 150 - 155
Pharmacokinetics and antitumor properties in tumor-bearing mice of an enediol analogue inhibitor of glyoxalase I Ellyn M. SharkeyHugh B. O'NeillJulie L. Eiseman ORIGINAL ARTICLE Pages: 156 - 166
Carzelesin phase II study in advanced breast, ovarian, colorectal, gastric, head and neck cancer, non-Hodgkin's lymphoma and malignant melanoma: a study of the EORTC early clinical studies group (ECSG) Nicholas PavlidisSteinar AamdalAxel-R. Hanauske CLINICAL TRIAL REPORT Pages: 167 - 171